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On the minimax robustness against correlation and heteroscedasticity of ordinary least squares among generalized least squares estimates of regression

普通最小二乘在广义最小二乘类中对相关性与异方差的极小极大稳健性

Summary We revisit a result according to which certain functions of covariance matrices are maximized at scalar multiples of the identity matrix. In a statistical context in which such functions measure loss, this says that the least favourable form of dependence is in fact independence, so that a procedure optimal for independent and identically distributed data can be minimax. In particular, the ordinary least squares estimate of a correctly specified regression response…

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Nonparametric data segmentation in multivariate time series via joint characteristic functions

利用联合特征函数对多元时间序列进行非参数分段

Summary Modern time series data often exhibit complex dependence and structural changes that are not easily characterized by shifts in the mean or model parameters. We propose a nonparametric data segmentation methodology for multivariate time series. By considering joint characteristic functions between the time series and its lagged values, our proposed method is able to detect changepoints in the marginal distribution, but also those in possibly nonlinear serial…

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Bayesian inference for generalized linear models via quasi-posteriors

通过拟后验进行广义线性模型的贝叶斯推断

Summary Generalized linear models are routinely used for modelling relationships between a response variable and a set of covariates. The simple form of a generalized linear model comes with easy interpretability, but also leads to concerns about model misspecification impacting inferential conclusions. A popular semiparametric solution adopted in the frequentist literature is quasilikelihood, which improves robustness by only requiring correct specification of the first two…

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An improved estimator of the pair correlation function of a spatial point process

空间点过程对相关函数的改进估计量

SUMMARY The pair correlation function, or two-point correlation, of a spatial point process is a fundamental tool in spatial statistics and astrostatistics, measuring the strength of spatial dependence between points. Interest is focused on the behaviour of this function at short distances, but this is the region in which existing estimators can be particularly unreliable. We propose a new estimator of the pair correlation function based on techniques from stochastic…

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On the fundamental limitations of multi-proposal Markov chain Monte Carlo algorithms

多候选马尔可夫链蒙特卡洛算法的基本局限

Summary We study multi-proposal Markov chain Monte Carlo algorithms, such as multiple-try or generalized Metropolis–Hastings schemes, which have recently received renewed attention due to their amenability to parallel computing. First, we prove that no multi-proposal scheme can speed up convergence relative to the corresponding single-proposal scheme by more than a factor of $ K $, where $ K $ denotes the number of proposals at each iteration. This result applies to…

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Continuous-time locally stationary wavelet processes

连续时间局部平稳小波过程

Abstract This article introduces the class of continuous-time locally stationary wavelet processes. Continuous-time models enable us to properly provide scale-based time series models for irregularly spaced observations for the first time, while also permitting a spectral representation of the process over a continuous range of scales. We derive results for both the theoretical setting, where we assume access to the entire process sample path, and a more practical one, which…

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Efficient estimation for functional accelerated failure time models

函数型加速失效时间模型的有效估计

Summary We propose a functional accelerated failure time model to characterize the effects of both functional and scalar covariates on the time to event of interest, and provide regularity conditions to guarantee model identifiability. For efficient estimation of model parameters, we develop a sieve maximum likelihood approach where parametric and nonparametric coefficients are bundled with an unknown baseline hazard function in the likelihood function. Not only do the…

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Sample splitting and assessing goodness-of-fit of time series

样本分割与时间序列拟合优度评估

Summary A fundamental and often final step in time series modelling is to assess the quality of fit of a proposed model to the data. Since the underlying distribution of the innovations that generate a model is often not prescribed, goodness-of-fit tests typically take the form of testing the fitted residuals for serial independence. However, these fitted residuals are intrinsically dependent since they are based on the same parameter estimates, and thus standard tests of…

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On the partial autocorrelation function for locally stationary time series: characterization, estimation and inference

局部平稳时间序列的偏自相关函数:刻画、估计与推断

SUMMARY For stationary time series, it is common to use plots of the partial autocorrelation function (PACF) or PACF-based tests to explore the temporal dependence structure of the process. To the best of our knowledge, analogues for nonstationary time series have not yet been fully developed. This article aims to fill this gap for locally stationary time series with short-range dependence. First, we characterize the PACF locally in the time domain and show that the jth PACF…

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Randomization inference when N equals one

样本单位数为一时的随机化推断

Summary For decades, $ N $-of-1 experiments, where a unit serves as its own control and treatment in different time windows, have been used in certain medical contexts. However, due to effects that accumulate over long time windows and interventions that have complex evolution, a lack of robust inference tools has limited the widespread applicability of such $ N $-of-1 designs. This work combines techniques from experimental design in causal inference and system…

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Noise-induced randomization in regression discontinuity designs

断点回归设计中由噪声诱导的随机化

Summary Regression discontinuity designs assess causal effects in settings where treatment is determined by whether an observed running variable crosses a prespecified threshold. Here, we propose a new approach to identification, estimation and inference in regression discontinuity designs that uses knowledge about exogenous noise (e.g., measurement error) in the running variable. In our strategy, we weight treated and control units to balance a latent variable, of which the…

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Testable implications of outcome-independent missingness not at random in covariates

协变量中与结局独立的非随机缺失:可检验含义

Summary A common aim of empirical research is to regress an outcome on a set of covariates, when some covariates are subject to missingness. If the probability of missingness is conditionally independent of the outcome, given the covariates, then a complete-case analysis is unbiased for parameters conditional on covariates. We derive all testable constraints that such outcome-independent missingness not at random implies on the observed data distribution, for settings where…

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Fast and reliable confidence intervals for a variance component

方差分量的快速可靠置信区间

Summary We show that in a variance component model, confidence intervals with asymptotically correct uniform coverage probability can be obtained by inverting certain test statistics based on the score for the restricted likelihood. The results hold in settings where the variance component is near or at the boundary of the parameter set. Simulations indicate that the proposed test statistics are approximately pivotal and lead to confidence intervals with near-nominal…

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Super-efficient estimation of future conditional hazards based on time-homogeneous high-quality marker information

基于时间齐次高质量标记信息的未来条件风险率超高效估计

Summary We introduce a new concept for forecasting future events based on marker information. The model is developed in the nonparametric counting process setting under the assumptions that the marker is of so-called high quality and with a time-homogeneous conditional distribution. Despite the model having nonparametric parts, it is established herein that it attains a parametric rate of uniform consistency and uniform asymptotic normality. In usual nonparametric scenarios,…

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Large-scale multiple testing of composite null hypotheses under heteroskedasticity

异方差下复合原假设的大规模多重检验

Summary Heteroskedasticity poses several methodological challenges in designing valid and powerful procedures for simultaneous testing of composite null hypotheses. In particular, the conventional practice of standardizing or rescaling heteroskedastic test statistics in this setting may severely affect the power of the underlying multiple testing procedure. Additionally, when the inferential parameter of interest is correlated with the variance of the test statistic, methods…

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Semiparametric sieve estimation for survival data with two-layer censoring

双层删失生存数据的半参数筛估计

Summary Disease registry data provide important information on the progression of disease conditions. However, reports of death or drop-out of patients enrolled in the registry are always subject to a noticeable delay. Reporting delays, together with the administrative censoring that arises from a freeze date in data collection, lead to two layers of right censoring in the data. The first layer results from random drop-out and acts on the survival time. The second layer is…

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An omitted variable bias framework for sensitivity analysis of instrumental variables

工具变量敏感性分析的遗漏变量偏误框架

Abstract We develop an omitted variable bias framework for sensitivity analysis of instrumental variable estimates that naturally handles multiple side effects (violations of the exclusion restriction assumption) and confounders (violations of the ignorability of the instrument assumption) of the instrument, exploits expert knowledge to bound sensitivity parameters and can be easily implemented with standard software. Specifically, we introduce sensitivity statistics for…

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Two-sample distribution tests in high dimensions via max-sliced Wasserstein distance and bootstrapping

基于最大切片 Wasserstein 距离与自助法的高维两样本分布检验

Summary Two-sample hypothesis testing is a fundamental statistical problem for inference about two populations. In this paper, we construct a novel test statistic to detect high-dimensional distributional differences based on the max-sliced Wasserstein distance to mitigate the curse of dimensionality. By exploiting an intriguing link between the distance and suprema of empirical processes, we develop an effective bootstrapping procedure to approximate the null distribution…

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Randomization-based Z -estimation for evaluating average and individual treatment effects

评估平均与个体处理效应的随机化 Z 估计

Summary Randomized experiments have been the gold standard for drawing causal inference. The conventional model-based approach has been one of the most popular methods of analysing treatment effects from randomized experiments, which is often carried out through inference for certain model parameters. In this paper, we provide a systematic investigation of model-based analyses for treatment effects under the randomization-based inference framework. This framework does not…

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Semiparametric local variable selection under misspecification

模型误设下的半参数局部变量选择

Summary Local variable selection aims to test for the effect of covariates on an outcome within specific regions. We outline a challenge that arises in the presence of nonlinear effects and model misspecification. Specifically, for common semiparametric methods, even slight model misspecification can result in a high false positive rate, in a manner that is highly sensitive to the chosen basis functions. We propose a method based on orthogonal cut splines that avoids false…

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Consistency of common spatial estimators under spatial confounding

空间混杂下常用空间估计量的一致性

Summary This article addresses the asymptotic performance of popular spatial regression estimators of the linear effect of an exposure on an outcome under spatial confounding, the presence of an unmeasured spatially structured variable influencing both the exposure and the outcome. We first show that the estimators from ordinary least squares and restricted spatial regression are asymptotically biased under spatial confounding. We then prove a novel result on the infill…

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Improving randomized controlled trial analysis via data-adaptive borrowing

通过数据自适应借用改进随机对照试验分析

Summary In recent years, real-world external controls have grown in popularity as a tool to empower randomized placebo-controlled trials, particularly in rare diseases or cases where balanced randomization is unethical or impractical. However, as external controls are not always comparable to the trials, direct borrowing without scrutiny may heavily bias the treatment effect estimator. Our paper proposes a data-adaptive integrative framework capable of preventing unknown…

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Partially factorized variational inference for high-dimensional mixed models

高维混合模型的部分因子化变分推断

Summary While generalized linear mixed models are a fundamental tool in applied statistics, many specifications, such as those involving categorical factors with many levels or interaction terms, can be computationally challenging to estimate due to the need to compute or approximate high-dimensional integrals. Variational inference is a popular way to perform such computations, especially in the Bayesian context. However, naive use of such methods can provide unreliable…

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Anytime-valid and asymptotically efficient inference driven by predictive recursion

预测递归驱动的随时有效且渐近高效推断

Summary Distinguishing two models is a fundamental and practically important statistical problem. Error rate control is crucial to the testing logic, but in complex nonparametric settings can be difficult to achieve, especially when the stopping rule that determines the data collection process is not available. This paper proposes an $ e $-process construction based on the predictive recursion algorithm originally designed to recursively fit nonparametric mixture models. The…

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