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Latin hypercube designs with controlled correlations and multi-dimensional stratification

兼具相关性控制与多维分层的拉丁超立方设计

Various methods have been proposed to construct Latin hypercube designs with small correlations. Orthogonal arrays have been used to construct Latin hypercube designs with multi-dimensional stratification. To integrate these two ideas, we propose a method to construct Latin hypercube designs with both controlled correlations and multi-dimensional stratification. For numerical integration, the constructed designs not only filter out lower-dimensional variance components as…

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Sequential combination of weighted and nonparametric bagging for classification

用于分类的加权与非参数袋装法的序贯组合

We propose a simple sequential procedure for bagged classification, which modifies nonparametric bagging by randomizing class labels of resampled data points. The random labelling feature of the procedure also enables us to undertake unsupervised classification with the benefit of supervised learning. Theoretical properties are given for the nearest neighbour classifier in the case of supervised learning and a hard-thresholding indicator in the case of unsupervised learning,…

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Convergence of sample eigenvalues, eigenvectors, and principal component scores for ultra-high dimensional data

超高维数据中样本特征值、特征向量与主成分得分的收敛

The development of high-throughput biomedical technologies has led to increased interest in the analysis of high-dimensional data where the number of features is much larger than the sample size. In this paper, we investigate principal component analysis under the ultra-high dimensional regime, where both the number of features and the sample size increase as the ratio of the two quantities also increases. We bridge the existing results from the finite and the high-dimension…

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Frequentist estimation of an epidemic's spreading potential when observations are scarce

观测稀少时流行病传播潜力的频率学派估计

We consider the problem of inferring the potential of an epidemic for escalating into a pandemic on the basis of limited observations in its initial stages. Classical results of Becker & Hasofer (J. R. Statist. Soc. B, 59, 415–29) illustrate that frequentist estimation of the complete set of parameters of an epidemic modelled as a birth and death process remains feasible even when one is able to observe only the deaths and the total number of births. These assumptions on the…

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Sparse precision matrix estimation via lasso penalized D-trace loss

基于 lasso 惩罚 D-trace 损失的稀疏精度矩阵估计

We introduce a constrained empirical loss minimization framework for estimating high-dimensional sparse precision matrices and propose a new loss function, called the D-trace loss, for that purpose. A novel sparse precision matrix estimator is defined as the minimizer of the lasso penalized D-trace loss under a positive-definiteness constraint. Under a new irrepresentability condition, the lasso penalized D-trace estimator is shown to have the sparse recovery property.…

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Model averaging and weight choice in linear mixed-effects models

线性混合效应模型中的模型平均与权重选择

This article studies model averaging for linear mixed-effects models. We establish an unbiased estimator of the squared risk for the model averaging, and use the estimator as a criterion for choosing weights. The resulting model average estimator is proved to be asymptotically optimal under some regularity conditions. Simulation experiments show it is superior or comparable to estimators based on the final models selected by the commonly-used methods and some existing…

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A sum characterization of hidden regular variation with likelihood inference via expectation-maximization

隐含正则变差的求和刻画与基于 EM 的似然推断

A fundamental deficiency of classical multivariate extreme value theory is the inability to distinguish between asymptotic independence and exact independence. In this work, we examine multivariate threshold modelling in the framework of regular variation on cones. Tail dependence is described by a limiting measure, which in some cases is degenerate on joint tail regions despite strong subasymptotic dependence in such regions. Hidden regular variation, a higher-order tail…

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Protective estimation of mixed-effects logistic regression when data are not missing at random

非随机缺失下混合效应逻辑回归的保护性估计

We consider estimation of mixed-effects logistic regression models for longitudinal data when missing outcomes are not missing at random. A typology of missingness mechanisms is presented that includes missingness dependent on observed or missing current outcomes, observed or missing lagged outcomes and subject-specific effects. When data are not missing at random, consistent estimation by maximum marginal likelihood generally requires correct parametric modelling of the…

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Graph estimation with joint additive models

基于联合加性模型的图估计

In recent years, there has been considerable interest in estimating conditional independence graphs in high dimensions. Most previous work has assumed that the variables are multivariate Gaussian, or that the conditional means of the variables are linear; in fact, these two assumptions are nearly equivalent. Unfortunately, if these assumptions are violated, the resulting conditional independence estimates can be inaccurate. We propose a semi-parametric method, graph…

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Retrospective-prospective symmetry in the likelihood and Bayesian analysis of case-control studies

病例对照研究中似然与贝叶斯分析的回顾—前瞻对称性

Prentice & Pyke (1979) established that the maximum likelihood estimate of an odds ratio in a case-control study is the same as would be found by fitting a logistic regression; in other words, for this specific target the incorrect prospective model is inferentially equivalent to the correct retrospective model.Similar results have been obtained for other models, and conditions have also been identified under which the corresponding Bayesian property holds, namely that the…

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On adjustment for auxiliary covariates in additive hazard models for the analysis of randomized experiments

随机实验中加性风险模型的辅助协变量调整

We consider additive hazard models (Aalen, 1989) for the effect of a randomized treatment on a survival outcome, adjusting for auxiliary baseline covariates. We demonstrate that the Aalen least squares estimator of the treatment effect parameter is asymptotically unbiased, even when the hazard's dependence on time or on the auxiliary covariates is misspecified, and even away from the null hypothesis of no treatment effect. We moreover show that adjustment for auxiliary…

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On the stationary distribution of iterative imputations

迭代插补的平稳分布

Iterative imputation, in which variables are imputed one at a time conditional on all the others, is a popular technique that can be convenient and flexible, as it replaces a potentially difficult multivariate modelling problem with relatively simple univariate regressions. In this paper, we begin to characterize the stationary distributions of iterative imputations and their statistical properties, accounting for the conditional models being iteratively estimated from data…

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Efficient inference for spatial extreme value processes associated to log-Gaussian random functions

与对数高斯随机函数相关的空间极值过程的高效推断

Max-stable processes arise as the only possible nontrivial limits for maxima of affinely normalized identically distributed stochastic processes, and thus form an important class of models for the extreme values of spatial processes. Until recently, inference for max-stable processes has been restricted to the use of pairwise composite likelihoods, due to intractability of higher-dimensional distributions. In this work we consider random fields that are in the domain of…

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Better subset regression

改进的子集回归

This paper studies the relationship between model fitting and screening performance to find efficient screening methods for high-dimensional linear regression models. Under a sparsity assumption we show in a general asymptotic setting that a subset that includes the true submodel always yields a smaller residual sum of squares than those that do not. To seek such a subset, we consider the optimization problem associated with best subset regression. An em algorithm, known as…

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Information criteria for variable selection under sparsity

稀疏情形下用于变量选择的信息准则

The optimization of an information criterion in a variable selection procedure leads to an additional bias, which can be substantial for sparse, high-dimensional data. One can compensate for the bias by applying shrinkage while estimating within the selected models. This paper presents modified information criteria for use in variable selection and estimation without shrinkage. The analysis motivating the modified criteria follows two routes. The first, which we explore for…

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Nonparametric estimation of a periodic sequence in the presence of a smooth trend

存在平滑趋势时周期序列的非参数估计

We investigate a nonparametric regression model including a periodic component, a smooth trend function, and a stochastic error term. We propose a procedure to estimate the unknown period and the function values of the periodic component as well as the nonparametric trend function. The theoretical part of the paper establishes the asymptotic properties of our estimators. In particular, we show that our estimator of the period is consistent. In addition, we derive the…

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Asymptotic properties for combined L1 and concave regularization

联合 L1 与凹惩罚正则化的渐近性质

Two important goals of high-dimensional modelling are prediction and variable selection. In this article, we consider regularization with combined L1 and concave penalties, and study the sampling properties of the global optimum of the suggested method in ultrahigh-dimensional settings. The L1 penalty provides the minimum regularization needed for removing noise variables in order to achieve oracle prediction risk, while a concave penalty imposes additional regularization to…

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Multivariate sign-based high-dimensional tests for sphericity

基于多元符号的高维球形性检验

This article concerns tests for sphericity in cases where the data dimension is larger than the sample size. The existing multivariate sign-based procedure (Hallin & Paindaveine, 2006) for sphericity is not robust with respect to high dimensionality, producing tests with Type I error rates that are much larger than the nominal levels. This is mainly due to bias from estimating the location parameter. We develop a correction that makes the existing test statistic robust with…

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Identifiability of Gaussian structural equation models with equal error variances

等误差方差高斯结构方程模型的可识别性

We consider structural equation models in which variables can be written as a function of their parents and noise terms, which are assumed to be jointly independent. Corresponding to each structural equation model is a directed acyclic graph describing the relationships between the variables. In Gaussian structural equation models with linear functions, the graph can be identified from the joint distribution only up to Markov equivalence classes, assuming faithfulness. In…

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Semiparametric estimation for the additive hazards model with left-truncated and right-censored data

左截断与右删失数据下加性风险模型的半参数估计

Survival data from prevalent cases collected under a cross-sectional sampling scheme are subject to left-truncation. When fitting an additive hazards model to left-truncated data, the conditional estimating equation method (Lin & Ying, 1994), obtained by modifying the risk sets to account for left-truncation, can be very inefficient, as the marginal likelihood of the truncation times is not used in the estimation procedure. In this paper, we use a pairwise pseudolikelihood…

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A simple test for random effects in regression models

回归模型中随机效应的简单检验

Testing that random effects are zero is difficult, because the null hypothesis restricts the corresponding variance parameter to the edge of the feasible parameter space. In the context of generalized linear mixed models, this paper exploits the link between random effects and penalized regression to develop a simple test for a zero effect. The idea is to treat the variance components not being tested as fixed at their estimates and then to express the likelihood ratio as a…

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Nonparametric Bayes modelling of count processes

计数过程的非参数贝叶斯建模

Data on count processes arise in a variety of applications, including longitudinal, spatial and imaging studies measuring count responses. The literature on statistical models for dependent count data is dominated by models built from hierarchical Poisson components. The Poisson assumption is not warranted in many applied contexts, and hierarchical Poisson models make restrictive assumptions about overdispersion in marginal distributions. In this article we propose a class…

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