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网络数据中协变量的降维AI 解读

Summary A problem of major interest in network data analysis is to explain the strength of connections using context information. To achieve this, we introduce a novel approach, called network-supervised dimension reduction, in which covariates are projected onto low-dimensional spaces to reveal the linkage pattern without assuming a model. We propose a new loss function for estimating the parameters in the resulting linear projection, based on the notion that closer…

误设广义线性模型中的大规模模型选择AI 解读

Summary Model selection is crucial both to high-dimensional learning and to inference for contemporary big data applications in pinpointing the best set of covariates among a sequence of candidate interpretable models. Most existing work implicitly assumes that the models are correctly specified or have fixed dimensionality, yet both model misspecification and high dimensionality are prevalent in practice. In this paper, we exploit the framework of model selection principles…

极值指数的分布式推断AI 解读

Summary In this paper we investigate a divide-and-conquer algorithm for estimating the extreme value index when data are stored in multiple machines. The oracle property of such an algorithm based on extreme value methods is not guaranteed by the general theory of distributed inference. We propose a distributed Hill estimator and establish its asymptotic theories. We consider various cases where the number of observations involved in each machine can be either homogeneous or…

广义结构模型中的回代检验AI 解读

Summary We introduce bootstrap tests for semiparametric generalized structured models. These can be used for testing different kinds of model specifications like separability, functional forms and homogeneity of effects, or for performing variable selection in a large class of semiparametric models. The test statistics are based on the comparison of non- and semiparametric alternatives in which both the null hypothesis and the alternative are non- or semiparametric. All…

随访不足时 Gumbel 最大吸引域分布的治愈比例估计AI 解读

Summary Estimators of the cured proportion from survival data which may include observations on cured subjects can only be expected to perform well when the follow-up period is sufficient. When follow-up is not sufficient, and the survival distribution of those susceptible to the event belongs to the Fréchet maximum domain of attraction, a nonparametric estimator for the cure proportion proposed by Escobar-Bach & Van Keilegom (2019) incorporates an adjustment that reduces…

《事件史与拓扑数据分析》讨论AI 解读

Summary Garside et al. (2021) use event history methods to analyse topological data. We provide additional background on persistent homology to contrast the hazard estimators used in Garside et al. (2021) with standard approaches in topological data analysis. In particular, Garside et al.’s approach is a local method, which has advantages and disadvantages, whereas homology is global. We also provide more details on persistence landscapes and show how a more complete use of…

二元工具变量模型下局部处理效应的估计AI 解读

Summary Instrumental variables are widely used to deal with unmeasured confounding in observational studies and imperfect randomized controlled trials. In these studies, researchers often target the so-called local average treatment effect as it is identifiable under mild conditions. In this paper we consider estimation of the local average treatment effect under the binary instrumental variable model. We discuss the challenges of causal estimation with a binary outcome and…

基于排列的贪婪因果推断算法的一致性保证AI 解读

Summary Directed acyclic graphical models are widely used to represent complex causal systems. Since the basic task of learning such a model from data is NP-hard, a standard approach is greedy search over the space of directed acyclic graphs or Markov equivalence classes of directed acyclic graphs. As the space of directed acyclic graphs on $p$ nodes and the associated space of Markov equivalence classes are both much larger than the space of permutations, it is desirable to…

协变量数量增长时完全随机实验中的回归调整AI 解读

Summary Randomized experiments have become important tools in empirical research. In a completely randomized treatment-control experiment, the simple difference in means of the outcome is un- biased for the average treatment effect, and covariate adjustment can further improve the efficiency without assuming a correctly specified outcome model. In modern applications, experimenters often have access to many covariates, motivating the need for a theory of covariate adjustment…

尺度未知时多元正态均值向量的可容许估计量AI 解读

Summary We study admissibility of a subclass of generalized Bayes estimators of a multivariate normal vector in the case where the variance is unknown, under scaled quadratic loss. Minimaxity is established for some of these estimators.

连续处理下工具变量有效性的不可检验性AI 解读

Summary This note presents a proof of the conjecture in Pearl (1995) about testing the validity of an instrumental variable in hidden variable models. It implies that instrument validity cannot be tested in the case where the endogenous treatment is continuously distributed. This stands in contrast to the classical testability results for instrument validity when the treatment is discrete. However, imposing weak structural assumptions on the model, such as continuity between…

疫苗试验主替代指标评价中缺失协变量下的变点推断AI 解读

Summary We consider the use of threshold-based regression models to evaluate immune response biomarkers as principal surrogate markers of a vaccine’s protective effect. Threshold-based regression models, which allow the relationship between a clinical outcome and a covariate to change dramatically across a threshold value in the covariate, have been studied by various authors under fully observed data. Limited research, however, has examined these models in the presence of…

学习基于 U 统计量的矩阵块结构AI 解读

Summary We introduce a conceptually simple, efficient and easily implemented approach for learning the block structure in a large matrix. Using the properties of U-statistics and large-dimensional random matrix theory, the group structure of many variables can be directly identified based on the eigenvalues and eigenvectors of the scaled sample matrix. We also establish the asymptotic properties of the proposed approach under mild conditions. The finite-sample performance of…

全基因组关联研究中协变量自适应的族错误率控制AI 解读

Summary The familywise error rate has been widely used in genome-wide association studies. With the increasing availability of functional genomics data, it is possible to increase detection power by leveraging these genomic functional annotations. Previous efforts to accommodate covariates in multiple testing focused on false discovery rate control, while covariate-adaptive procedures controlling the familywise error rate remain underdeveloped. Here, we propose a novel…

事件史方法与拓扑数据分析AI 解读

Summary Persistent homology is used to track the appearance and disappearance of features as we move through a nested sequence of topological spaces. Equating the nested sequence to a filtration and the appearance and disappearance of features to events, we show that simple event history methods can be used for the analysis of topological data. We propose a version of the well-known Nelson–Aalen cumulative hazard estimator for the comparison of topological features of random…

基于最大偏差的函数型数据生物等效性检验AI 解读

Summary We study the problem of testing equivalence of functional parameters, such as the mean or the variance function, in the two-sample functional data setting. In contrast to previous work where the functional problem is reduced to a multiple testing problem for the equivalence of scalar data by comparing the functions at each point, our approach is based on an estimate of a distance measuring the maximum deviation between the two functional parameters. Equivalence is…

面板计数数据半参数回归模型的最大似然估计AI 解读

Summary Panel count data, in which the observation for each study subject consists of the number of recurrent events between successive examinations, are commonly encountered in industrial reliability testing, medical research and other scientific investigations. We formulate the effects of potentially time-dependent covariates on one or more types of recurrent events through nonhomogeneous Poisson processes with random effects. We employ nonparametric maximum likelihood…

依赖删失生存数据的半参数建模、估计与推断AI 解读

Summary When modelling survival data, it is common to assume that the survival time $T$ is conditionally independent of the censoring time $C$ given a set of covariates. However, there are numerous situations in which this assumption is not realistic. The goal of this paper is therefore to develop a semiparametric normal transformation model which assumes that, after a proper nonparametric monotone transformation, the vector $(T, C)$ follows a linear model, and the vector of…

统计泛函的可诱导复杂度AI 解读

Summary A property, or statistical functional, is said to be elicitable if it minimizes the expected loss for some loss function. The study of which properties are elicitable sheds light on the capabilities and limitations of point estimation and empirical risk minimization. While recent work has sought to identify which properties are elicitable, here we investigate a more nuanced question: how many dimensions are required to indirectly elicit a given property? This number…

交叉验证带宽的袋装聚合及其大数据应用AI 解读

Summary Hall & Robinson (2009) proposed and analysed the use of bagged cross-validation to choose the bandwidth of a kernel density estimator. They established that bagging greatly reduces the noise inherent in ordinary cross-validation, and hence leads to a more efficient bandwidth selector. The asymptotic theory of Hall & Robinson (2009) assumes that $N$, the number of bagged subsamples, is $\infty$. We expand upon their theoretical results by allowing $N$ to be finite, as…

《移动健康中二元结局的时变因果偏离效应估计》讨论AI 解读

Summary In this discussion, we examine the contributions of Qian et al. (2021) and potential applications of the newly developed estimator for the causal excursion effect in binary outcome data. Specifically, we consider extension of their method to count outcomes and observational data, propose an alternative use of their method for analysing excursion effect trajectories and discuss ways of improving estimator efficiency.

通过类 Gibbs 步骤实现逐分量近似贝叶斯计算AI 解读

Summary Approximate Bayesian computation methods are useful for generative models with intractable likelihoods. These methods are, however, sensitive to the dimension of the parameter space, requiring exponentially increasing resources as this dimension grows. To tackle this difficulty we explore a Gibbs version of the approximate Bayesian computation approach that runs component-wise approximate Bayesian computation steps aimed at the corresponding conditional posterior…

函数型短片段数据的基展开方法AI 解读

Summary Estimation of mean and covariance functions is fundamental for functional data analysis. While this topic has been studied extensively in the literature, a key assumption is that there are enough data in the domain of interest to estimate both the mean and covariance functions. We investigate mean and covariance estimation for functional snippets in which observations from a subject are available only in an interval of length strictly, and often much, shorter than…

通过降维构建简约的个性化剂量探索模型AI 解读

Summary Learning an individualized dose rule in personalized medicine is a challenging statistical problem. Existing methods often suffer from the curse of dimensionality, especially when the decision function is estimated nonparametrically. To tackle this problem, we propose a dimension reduction framework that effectively reduces the estimation to an optimization on a lower-dimensional subspace of the covariates. We exploit the fact that the individualized dose rule can be…