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Bayesian learning of network structures from interventional experimental data

利用干预实验数据贝叶斯学习网络结构

Summary Directed acyclic graphs provide an effective framework for learning causal relationships among variables given multivariate observations. Under pure observational data, directed acyclic graphs encoding the same conditional independencies cannot be distinguished and are collected into Markov equivalence classes. In many contexts, however, observational measurements are supplemented by interventional data that improve directed acyclic graph identifiability and enhance…

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Universal robust regression via maximum mean discrepancy

基于最大均值差异的通用稳健回归

Abstract Many modern datasets are collected automatically and are thus easily contaminated by outliers. This has led to a renewed interest in robust estimation, including new notions of robustness such as robustness to adversarial contamination of the data. However, most robust estimation methods are designed for a specific model. Notably, many methods were proposed recently to obtain robust estimators in linear models, or generalized linear models, and a few were developed…

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Treatment effect quantiles in stratified randomized experiments and matched observational studies

分层随机实验与匹配观察研究中的个体处理效应分位数

Summary Evaluating the treatment effect has become an important topic for many applications. However, most existing literature focuses mainly on average treatment effects. When the individual effects are heavy tailed or have outlier values, not only may the average effect not be appropriate for summarizing treatment effects, but also the conventional inference for it can be sensitive and possibly invalid due to poor large-sample approximations. In this paper we focus on…

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Characterizing M -estimators

M估计量的刻画

Summary We characterize the full classes of M-estimators for semiparametric models of general functionals by formally connecting the theory of consistent loss functions from forecast evaluation with the theory of M-estimation. This novel characterization result allows us to leverage existing results on loss functions known from the literature on forecast evaluation in estimation theory. We exemplify advantageous implications for the fields of robust, efficient, equivariant…

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Power and sample size calculations for rerandomization

再随机化设计的检验功效与样本量计算

Summary Power analyses are an important aspect of experimental design, because they help determine how experiments are implemented in practice. It is common to specify a desired level of power and compute the sample size necessary to obtain that power. Such calculations are well known for completely randomized experiments, but there can be many benefits to using other experimental designs. For example, it has recently been established that rerandomization, where subjects are…

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Statistical summaries of unlabelled evolutionary trees

无标签演化树的统计摘要

Summary Rooted and ranked phylogenetic trees are mathematical objects that are useful in modelling hierarchical data and evolutionary relationships with applications to many fields such as evolutionary biology and genetic epidemiology. Bayesian phylogenetic inference usually explores the posterior distribution of trees via Markov chain Monte Carlo methods. However, assessing uncertainty and summarizing distributions remains challenging for these types of structures. While…

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Populations of unlabelled networks: graph space geometry and generalized geodesic principal components

无标签网络总体:图空间几何与广义测地主成分

Abstract Statistical analysis for populations of networks is widely applicable, but challenging, as networks have strongly non-Euclidean behaviour. Graph space is an exhaustive framework for studying populations of unlabelled networks that are weighted or unweighted, uni- or multilayered, directed or undirected. Viewing graph space as the quotient of a Euclidean space with respect to a finite group action, we show that it is not a manifold, and that its curvature is…

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Tailored inference for finite populations: conditional validity and transfer across distributions

面向有限总体的定制推断:条件有效性与跨分布迁移

Summary Parameters of subpopulations can be more relevant than those of superpopulations. For example, a healthcare provider may be interested in the effect of a treatment plan for a specific subset of their patients; policymakers may be concerned with the impact of a policy in a particular state within a given population. In these cases, the focus is on a specific finite population, as opposed to an infinite superpopulation. Such a population can be characterized by fixing…

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Hybrid confidence intervals for informative uniform asymptotic inference after model selection

模型选择后兼具信息量与一致渐近有效性的混合置信区间

Abstract I propose a new type of confidence interval for correct asymptotic inference after using data to select a model of interest without assuming any model is correctly specified. This hybrid confidence interval is constructed by combining techniques from the selective inference and post-selection inference literatures to yield a short confidence interval across a wide range of data realizations. I show that hybrid confidence intervals have correct asymptotic coverage,…

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Scalable subsampling: computation, aggregation and inference

可扩展子抽样:计算、聚合与推断

Abstract Subsampling has seen a resurgence in the big data era where the standard, full-resample size bootstrap can be infeasible to compute. Nevertheless, even choosing a single random subsample of size b can be computationally challenging with both b and the sample size n being very large. This paper shows how a set of appropriately chosen, nonrandom subsamples can be used to conduct effective, and computationally feasible, subsampling distribution estimation. Furthermore,…

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Causal inference with misspecified exposure mappings: separating definitions and assumptions

暴露映射误设下的因果推断:分离定义与假设

Summary Exposure mappings facilitate investigations of complex causal effects when units interact in experiments. Current methods require experimenters to use the same exposure mappings to define the effect of interest and to impose assumptions on the interference structure. However, the two roles rarely coincide in practice, and experimenters are forced to make the often questionable assumption that their exposures are correctly specified. This paper argues that the two…

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Rejoinder: ‘Statistical inference for streamed longitudinal data’

《流式纵向数据的统计推断》讨论回复

We thank the editorial board for organizing this discussion and giving us the opportunity to explore experts’ perspectives on our work. We sincerely appreciate the discussants for their insightful contributions, which have raised many important points and provided suggestions for potential improvements and generalizations of our proposed method. In this rejoinder, we primarily focus on three important aspects raised by the discussants: (i) the role of the weighting parameter…

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Discussion of ‘Statistical inference for streamed longitudinal data’

对《流式纵向数据的统计推断》的讨论

We congratulate the authors for their contributions to statistical analysis for streamed longitudinal data. Streamed data occur frequently in many modern biomedical areas such as mobile health, drawing increasing attention in recent years. Luo et al. (2023) developed a new statistical inference framework for streamed longitudinal data via the quadratic inference function approach. The proposed method avoids retrospective calculations using the individual-level data in the…

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√2-estimation for smooth eigenvectors of matrix-valued functions

矩阵值函数平滑特征向量的√2估计

Summary Modern statistical methods for multivariate time series rely on the eigendecomposition of matrix-valued functions such as time-varying covariance and spectral density matrices. The curse of indeterminacy or misidentification of smooth eigenvector functions has not received much attention. We resolve this important problem and recover smooth trajectories by examining the distance between the eigenvectors of the same matrix-valued function evaluated at two consecutive…

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Targeted optimal treatment regime learning using summary statistics

利用汇总统计量学习面向目标总体的最优治疗规则

Summary Personalized decision-making, aiming to derive optimal treatment regimes based on individual characteristics, has recently attracted increasing attention in many fields, such as medicine, social services and economics. Current literature mainly focuses on estimating treatment regimes from a single source population. In real-world applications, the distribution of a target population can be different from that of the source population. Therefore, treatment regimes…

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Ancestor regression in linear structural equation models

线性结构方程模型中的祖先回归

Summary We present a new method for causal discovery in linear structural equation models. We propose a simple technique based on statistical testing in linear models that can distinguish between ancestors and non-ancestors of any given variable. Naturally, this approach can then be extended to estimating the causal order among all variables. We provide explicit error control for false causal discovery, at least asymptotically. This holds true even under Gaussianity, where…

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A robust fusion-extraction procedure with summary statistics in the presence of biased sources

存在有偏来源时基于汇总统计量的稳健融合与提取

Summary Information from multiple data sources is increasingly available. However, some data sources may produce biased estimates due to biased sampling, data corruption or model misspecification. Thus there is a need for robust data combination methods that can be used with biased sources. In this paper, a robust data fusion-extraction method is proposed. Unlike existing methods, the proposed method can be applied in the important case where researchers have no knowledge of…

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Semiparametric counterfactual density estimation

反事实密度的半参数估计

Abstract Causal effects are often characterized with averages, which can give an incomplete picture of the underlying counterfactual distributions. Here we consider estimating the entire counterfactual density and generic functionals thereof. We focus on two kinds of target parameters: density approximations and the distance between counterfactual densities. We study nonparametric efficiency bounds, giving results for smooth but otherwise generic models and distances.…

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Proximal mediation analysis

近端中介分析

Summary A common concern when trying to draw causal inferences from observational data is that the measured covariates are insufficiently rich to account for all sources of confounding. In practice, many of the covariates may only be proxies of the latent confounding mechanism. Recent work has shown that in certain settings where the standard no-unmeasured-confounding assumption fails, proxy variables can be leveraged to identify causal effects. Results currently exist for…

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Soft calibration for selection bias problems under mixed-effects models

混合效应模型下应对选择偏差的软校准

Abstract Calibration weighting has been widely used to correct selection biases in nonprobability sampling, missing data and causal inference. The main idea is to calibrate the biased sample to the benchmark by adjusting the subject weights. However, hard calibration can produce enormous weights when an exact calibration is enforced on a large set of extraneous covariates. This article proposes a soft calibration scheme, where the outcome and the selection indicator follow…

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Nonparametric estimation of the intensity function of a spatial point process on a Riemannian manifold

黎曼流形上空间点过程强度函数的非参数估计

Summary This paper is concerned with nonparametric estimation of the intensity function of a point process on a Riemannian manifold. It provides a first-order asymptotic analysis of the proposed kernel estimator for Poisson processes, supplemented by empirical work to probe the behaviour in finite samples and under other generative regimes. The investigation highlights the scope for finite-sample improvements by allowing the bandwidth to adapt to local curvature.

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Equivariant estimation of Fréchet means

Fréchet均值的等变估计

Summary The Fréchet mean generalizes the concept of a mean to a metric space setting. In this work we consider equivariant estimation of Fréchet means for parametric models on metric spaces that are Riemannian manifolds. The geometry and symmetry of such a space are partially encoded by its isometry group of distance-preserving transformations. Estimators that are equivariant under the isometry group take into account the symmetry of the metric space. For some models, there…

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