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Learning loopy graphical models with latent variables: Efficient methods and guarantees

含潜变量的有环图模型学习:高效方法与理论保证

The problem of structure estimation in graphical models with latent variables is considered. We characterize conditions for tractable graph estimation and develop efficient methods with provable guarantees. We consider models where the underlying Markov graph is locally tree-like, and the model is in the regime of correlation decay. For the special case of the Ising model, the number of samples $n$ required for structural consistency of our method scales as $n=\Omega(\theta_{\min}^{-\delta\eta(\eta+1)-2}\log p)$…

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Exact and asymptotically robust permutation tests

精确且渐近稳健的置换检验

Given independent samples from $P$ and $Q$, two-sample permutation tests allow one to construct exact level tests when the null hypothesis is $P=Q$. On the other hand, when comparing or testing particular parameters $\theta$ of $P$ and $Q$, such as their means or medians, permutation tests need not be level $\alpha$, or even approximately level $\alpha$ in large samples. Under very weak assumptions for comparing estimators, we provide a general test procedure whereby the…

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Fiducial theory and optimal inference

信赖理论与最优推断

It is shown that the fiducial distribution in a group model, or more generally a quasigroup model, determines the optimal equivariant frequentist inference procedures. The proof does not rely on existence of invariant measures, and generalizes results corresponding to the choice of the right Haar measure as a Bayesian prior. Classical and more recent examples show that fiducial arguments can be used to give good candidates for exact or approximate confidence distributions.…

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A Cramér moderate deviation theorem for Hotelling’s $T^{2}$-statistic with applications to global tests

Hotelling T² 统计量的 Cramér 中偏差定理及全局检验应用

A Cramér moderate deviation theorem for Hotelling’s $T^{2}$-statistic is proved under a finite $(3+\delta)$th moment. The result is applied to large scale tests on the equality of mean vectors and is shown that the number of tests can be as large as $e^{o(n^{1/3})}$ before the chi-squared distribution calibration becomes inaccurate. As an application of the moderate deviation results, a global test on the equality of $m$ mean vectors based on the maximum of Hotelling’s $T^{2}$…

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Weighted likelihood estimation under two-phase sampling

两阶段抽样下的加权似然估计

We develop asymptotic theory for weighted likelihood estimators (WLE) under two-phase stratified sampling without replacement. We also consider several variants of WLEs involving estimated weights and calibration. A set of empirical process tools are developed including a Glivenko–Cantelli theorem, a theorem for rates of convergence of $M$-estimators, and a Donsker theorem for the inverse probability weighted empirical processes under two-phase sampling and sampling without…

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Efficient estimation in sufficient dimension reduction

充分降维中的有效估计

We develop an efficient estimation procedure for identifying and estimating the central subspace. Using a new way of parameterization, we convert the problem of identifying the central subspace to the problem of estimating a finite dimensional parameter in a semiparametric model. This conversion allows us to derive an efficient estimator which reaches the optimal semiparametric efficiency bound. The resulting efficient estimator can exhaustively estimate the central subspace…

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On the definition of a confounder

混杂变量的定义

The causal inference literature has provided a clear formal definition of confounding expressed in terms of counterfactual independence. The literature has not, however, come to any consensus on a formal definition of a confounder, as it has given priority to the concept of confounding over that of a confounder. We consider a number of candidate definitions arising from various more informal statements made in the literature. We consider the properties satisfied by each…

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Quantile-adaptive model-free variable screening for high-dimensional heterogeneous data

高维异质数据的分位数自适应无模型变量筛选

We introduce a quantile-adaptive framework for nonlinear variable screening with high-dimensional heterogeneous data. This framework has two distinctive features: (1) it allows the set of active variables to vary across quantiles, thus making it more flexible to accommodate heterogeneity; (2) it is model-free and avoids the difficult task of specifying the form of a statistical model in a high dimensional space. Our nonlinear independence screening procedure employs spline…

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A general theory for nonlinear sufficient dimension reduction: Formulation and estimation

非线性充分降维的一般理论:表述与估计

In this paper we introduce a general theory for nonlinear sufficient dimension reduction, and explore its ramifications and scope. This theory subsumes recent work employing reproducing kernel Hilbert spaces, and reveals many parallels between linear and nonlinear sufficient dimension reduction. Using these parallels we analyze the properties of existing methods and develop new ones. We begin by characterizing dimension reduction at the general level of $\sigma$-fields and…

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Convergence of latent mixing measures in finite and infinite mixture models

有限与无限混合模型中潜在混合测度的收敛

This paper studies convergence behavior of latent mixing measures that arise in finite and infinite mixture models, using transportation distances (i.e., Wasserstein metrics). The relationship between Wasserstein distances on the space of mixing measures and $f$-divergence functionals such as Hellinger and Kullback–Leibler distances on the space of mixture distributions is investigated in detail using various identifiability conditions. Convergence in Wasserstein metrics for…

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An algorithm to compute the power of Monte Carlo tests with guaranteed precision

保证精度的蒙特卡洛检验功效计算算法

This article presents an algorithm that generates a conservative confidence interval of a specified length and coverage probability for the power of a Monte Carlo test (such as a bootstrap or permutation test). It is the first method that achieves this aim for almost any Monte Carlo test. Previous research has focused on obtaining as accurate a result as possible for a fixed computational effort, without providing a guaranteed precision in the above sense. The algorithm we…

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Convergence rate of Markov chain methods for genomic motif discovery

基因组模体发现中马尔可夫链方法的收敛速度

We analyze the convergence rate of a simplified version of a popular Gibbs sampling method used for statistical discovery of gene regulatory binding motifs in DNA sequences. This sampler satisfies a very strong form of ergodicity (uniform). However, we show that, due to multimodality of the posterior distribution, the rate of convergence often decreases exponentially as a function of the length of the DNA sequence. Specifically, we show that this occurs whenever there is…

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Spatially-adaptive sensing in nonparametric regression

非参数回归中的空间自适应采样

While adaptive sensing has provided improved rates of convergence in sparse regression and classification, results in nonparametric regression have so far been restricted to quite specific classes of functions. In this paper, we describe an adaptive-sensing algorithm which is applicable to general nonparametric-regression problems. The algorithm is spatially adaptive, and achieves improved rates of convergence over spatially inhomogeneous functions. Over standard function…

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The linear stochastic order and directed inference for multivariate ordered distributions

线性随机序与多元有序分布的定向推断

Researchers are often interested in drawing inferences regarding the order between two experimental groups on the basis of multivariate response data. Since standard multivariate methods are designed for two sided alternatives they may not be ideal for testing for order between two groups. In this article we introduce the notion of the linear stochastic order and investigate its properties. Statistical theory and methodology are developed to both estimate the direction which…

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Improved multivariate normal mean estimation with unknown covariance when $p$ is greater than $n$

维数大于自由度时未知协方差下的多元正态均值改进估计

We consider the problem of estimating the mean vector of a $p$-variate normal $(\theta,\Sigma)$ distribution under invariant quadratic loss, $(\delta-\theta)'\Sigma^{-1}(\delta-\theta)$, when the covariance is unknown. We propose a new class of estimators that dominate the usual estimator $\delta^{0}(X)=X$. The proposed estimators of $\theta$ depend upon $X$ and an independent Wishart matrix $S$ with $n$ degrees of freedom, however, $S$ is singular almost surely when $p>n$.…

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Estimation in functional linear quantile regression

函数型线性分位数回归中的估计

This paper studies estimation in functional linear quantile regression in which the dependent variable is scalar while the covariate is a function, and the conditional quantile for each fixed quantile index is modeled as a linear functional of the covariate. Here we suppose that covariates are discretely observed and sampling points may differ across subjects, where the number of measurements per subject increases as the sample size. Also, we allow the quantile index to vary…

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Accuracy guaranties for $\ell_{1}$ recovery of block-sparse signals

块稀疏信号 ℓ₁ 恢复的精度保证

We introduce a general framework to handle structured models (sparse and block-sparse with possibly overlapping blocks). We discuss new methods for their recovery from incomplete observation, corrupted with deterministic and stochastic noise, using block-$\ell_{1}$ regularization. While the current theory provides promising bounds for the recovery errors under a number of different, yet mostly hard to verify conditions, our emphasis is on verifiable conditions on the problem…

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Variable transformation to obtain geometric ergodicity in the random-walk Metropolis algorithm

通过变量变换使随机游走Metropolis算法几何遍历

A random-walk Metropolis sampler is geometrically ergodic if its equilibrium density is super-exponentially light and satisfies a curvature condition [Stochastic Process. Appl. 85 (2000) 341–361]. Many applications, including Bayesian analysis with conjugate priors of logistic and Poisson regression and of log-linear models for categorical data result in posterior distributions that are not super-exponentially light. We show how to apply the change-of-variable formula for…

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Asymptotic optimality and efficient computation of the leave-subject-out cross-validation

留受试者交叉验证的渐近最优性与高效计算

Although the leave-subject-out cross-validation (CV) has been widely used in practice for tuning parameter selection for various nonparametric and semiparametric models of longitudinal data, its theoretical property is unknown and solving the associated optimization problem is computationally expensive, especially when there are multiple tuning parameters. In this paper, by focusing on the penalized spline method, we show that the leave-subject-out CV is optimal in the sense…

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The transfer principle: A tool for complete case analysis

转移原理:完整案例分析的工具

This paper gives a general method for deriving limiting distributions of complete case statistics for missing data models from corresponding results for the model where all data are observed. This provides a convenient tool for obtaining the asymptotic behavior of complete case versions of established full data methods without lengthy proofs. The methodology is illustrated by analyzing three inference procedures for partially linear regression models with responses missing…

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Independent component analysis via nonparametric maximum likelihood estimation

基于非参数极大似然估计的独立成分分析

Independent Component Analysis (ICA) models are very popular semiparametric models in which we observe independent copies of a random vector $X=AS$, where $A$ is a non-singular matrix and $S$ has independent components. We propose a new way of estimating the unmixing matrix $W=A^{-1}$ and the marginal distributions of the components of $S$ using nonparametric maximum likelihood. Specifically, we study the projection of the empirical distribution onto the subset of ICA…

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Two-step spline estimating equations for generalized additive partially linear models with large cluster sizes

大簇样本下广义可加部分线性模型的两步样条估计方程

We propose a two-step estimating procedure for generalized additive partially linear models with clustered data using estimating equations. Our proposed method applies to the case that the number of observations per cluster is allowed to increase with the number of independent subjects. We establish oracle properties for the two-step estimator of each function component such that it performs as well as the univariate function estimator by assuming that the parametric vector…

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Rotation and scale space random fields and the Gaussian kinematic formula

旋转与尺度空间随机场及高斯运动学公式

We provide a new approach, along with extensions, to results in two important papers of Worsley, Siegmund and coworkers closely tied to the statistical analysis of fMRI (functional magnetic resonance imaging) brain data. These papers studied approximations for the exceedence probabilities of scale and rotation space random fields, the latter playing an important role in the statistical analysis of fMRI data. The techniques used there came either from the Euler characteristic…

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Optimal two-stage procedures for estimating location and size of the maximum of a multivariate regression function

估计多元回归函数最大值位置与大小的最优两阶段程序

We propose a two-stage procedure for estimating the location $\mathbf{\mu}$ and size $M$ of the maximum of a smooth $d$-variate regression function $f$. In the first stage, a preliminary estimator of $\mathbf{\mu}$ obtained from a standard nonparametric smoothing method is used. At the second stage, we “zoom-in” near the vicinity of the preliminary estimator and make further observations at some design points in that vicinity. We fit an appropriate polynomial regression…

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