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Optimal experimental designs for fMRI via circulant biased weighing designs

利用循环偏置称重设计构造最优 fMRI 实验

Functional magnetic resonance imaging (fMRI) technology is popularly used in many fields for studying how the brain reacts to mental stimuli. The identification of optimal fMRI experimental designs is crucial for rendering precise statistical inference on brain functions, but research on this topic is very lacking. We develop a general theory to guide the selection of fMRI designs for estimating a hemodynamic response function (HRF) that models the effect over time of the…

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Bootstrap and permutation tests of independence for point processes

点过程独立性的 Bootstrap 与置换检验

Motivated by a neuroscience question about synchrony detection in spike train analysis, we deal with the independence testing problem for point processes. We introduce nonparametric test statistics, which are rescaled general $U$-statistics, whose corresponding critical values are constructed from bootstrap and randomization/permutation approaches, making as few assumptions as possible on the underlying distribution of the point processes. We derive general consistency…

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Empirical risk minimization for heavy-tailed losses

重尾损失下的经验风险最小化

The purpose of this paper is to discuss empirical risk minimization when the losses are not necessarily bounded and may have a distribution with heavy tails. In such situations, usual empirical averages may fail to provide reliable estimates and empirical risk minimization may provide large excess risk. However, some robust mean estimators proposed in the literature may be used to replace empirical means. In this paper, we investigate empirical risk minimization based on a…

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Coupling methods for multistage sampling

多阶段抽样的耦合方法

Multistage sampling is commonly used for household surveys when there exists no sampling frame, or when the population is scattered over a wide area. Multistage sampling usually introduces a complex dependence in the selection of the final units, which makes asymptotic results quite difficult to prove. In this work, we consider multistage sampling with simple random without replacement sampling at the first stage, and with an arbitrary sampling design for further stages. We…

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Aggregation of predictors for nonstationary sub-linear processes and online adaptive forecasting of time varying autoregressive processes

非平稳次线性过程的预测器聚合与时变自回归过程的在线自适应预测

In this work, we study the problem of aggregating a finite number of predictors for nonstationary sub-linear processes. We provide oracle inequalities relying essentially on three ingredients: (1) a uniform bound of the $\ell^{1}$ norm of the time varying sub-linear coefficients, (2) a Lipschitz assumption on the predictors and (3) moment conditions on the noise appearing in the linear representation. Two kinds of aggregations are considered giving rise to different moment…

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A Bernstein–von Mises theorem for smooth functionals in semiparametric models

半参数模型中光滑泛函的 Bernstein–von Mises 定理

A Bernstein–von Mises theorem is derived for general semiparametric functionals. The result is applied to a variety of semiparametric problems in i.i.d. and non-i.i.d. situations. In particular, new tools are developed to handle semiparametric bias, in particular for nonlinear functionals and in cases where regularity is possibly low. Examples include the squared $L^{2}$-norm in Gaussian white noise, nonlinear functionals in density estimation, as well as functionals in…

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Rate-optimal graphon estimation

达到最优收敛率的 Graphon 估计

Network analysis is becoming one of the most active research areas in statistics. Significant advances have been made recently on developing theories, methodologies and algorithms for analyzing networks. However, there has been little fundamental study on optimal estimation. In this paper, we establish optimal rate of convergence for graphon estimation. For the stochastic block model with $k$ clusters, we show that the optimal rate under the mean squared error is $n^{-1}\log k+k^{2}/n^{2}$…

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Uniform change point tests in high dimension

高维情形下的同时变点检验

Consider $d$ dependent change point tests, each based on a CUSUM-statistic. We provide an asymptotic theory that allows us to deal with the maximum over all test statistics as both the sample size $n$ and $d$ tend to infinity. We achieve this either by a consistent bootstrap or an appropriate limit distribution. This allows for the construction of simultaneous confidence bands for dependent change point tests, and explicitly allows us to determine the location of the change…

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Subsampling bootstrap of count features of networks

网络计数特征的子抽样 Bootstrap

Analysis of stochastic models of networks is quite important in light of the huge influx of network data in social, information and bio sciences, but a proper statistical analysis of features of different stochastic models of networks is still underway. We propose bootstrap subsampling methods for finding empirical distribution of count features or “moments” (Bickel, Chen and Levina [Ann. Statist. 39 (2011) 2280–2301]) and smooth functions of these features for the networks.…

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Efficient calibration for imperfect computer models

不完美计算机模型的有效校准

Many computer models contain unknown parameters which need to be estimated using physical observations. Tuo and Wu (2014) show that the calibration method based on Gaussian process models proposed by Kennedy and O’Hagan [J. R. Stat. Soc. Ser. B. Stat. Methodol. 63 (2001) 425–464] may lead to an unreasonable estimate for imperfect computer models. In this work, we extend their study to calibration problems with stochastic physical data. We propose a novel method, called the $L_{2}$…

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On adaptive posterior concentration rates

自适应后验集中速率

We investigate the problem of deriving posterior concentration rates under different loss functions in nonparametric Bayes. We first provide a lower bound on posterior coverages of shrinking neighbourhoods that relates the metric or loss under which the shrinking neighbourhood is considered, and an intrinsic pre-metric linked to frequentist separation rates. In the Gaussian white noise model, we construct feasible priors based on a spike and slab procedure reminiscent of…

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Globally adaptive quantile regression with ultra-high dimensional data

超高维数据的全局自适应分位数回归

Quantile regression has become a valuable tool to analyze heterogeneous covaraite-response associations that are often encountered in practice. The development of quantile regression methodology for high-dimensional covariates primarily focuses on the examination of model sparsity at a single or multiple quantile levels, which are typically prespecified ad hoc by the users. The resulting models may be sensitive to the specific choices of the quantile levels, leading to…

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Minimax estimation in sparse canonical correlation analysis

稀疏典型相关分析中的极小极大估计

Canonical correlation analysis is a widely used multivariate statistical technique for exploring the relation between two sets of variables. This paper considers the problem of estimating the leading canonical correlation directions in high-dimensional settings. Recently, under the assumption that the leading canonical correlation directions are sparse, various procedures have been proposed for many high-dimensional applications involving massive data sets. However, there…

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Fully adaptive density-based clustering

完全自适应的密度聚类

The clusters of a distribution are often defined by the connected components of a density level set. However, this definition depends on the user-specified level. We address this issue by proposing a simple, generic algorithm, which uses an almost arbitrary level set estimator to estimate the smallest level at which there are more than one connected components. In the case where this algorithm is fed with histogram-based level set estimates, we provide a finite sample…

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Functional additive regression

函数型加性回归

We suggest a new method, called Functional Additive Regression, or FAR, for efficiently performing high-dimensional functional regression. FAR extends the usual linear regression model involving a functional predictor, $X(t)$, and a scalar response, $Y$, in two key respects. First, FAR uses a penalized least squares optimization approach to efficiently deal with high-dimensional problems involving a large number of functional predictors. Second, FAR extends beyond the…

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Estimation and inference in generalized additive coefficient models for nonlinear interactions with high-dimensional covariates

高维协变量非线性交互的广义加性系数模型估计与推断

In the low-dimensional case, the generalized additive coefficient model (GACM) proposed by Xue and Yang [Statist. Sinica 16 (2006) 1423–1446] has been demonstrated to be a powerful tool for studying nonlinear interaction effects of variables. In this paper, we propose estimation and inference procedures for the GACM when the dimension of the variables is high. Specifically, we propose a groupwise penalization based procedure to distinguish significant covariates for the…

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Adaptive testing on a regression function at a point

回归函数单点的自适应检验

We consider the problem of inference on a regression function at a point when the entire function satisfies a sign or shape restriction under the null. We propose a test that achieves the optimal minimax rate adaptively over a range of Hölder classes, up to a $\log\log n$ term, which we show to be necessary for adaptation. We apply the results to adaptive one-sided tests for the regression discontinuity parameter under a monotonicity restriction, the value of a monotone…

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Nonparametric confidence intervals for monotone functions

单调函数的非参数置信区间

We study nonparametric isotonic confidence intervals for monotone functions. In [Ann. Statist. 29 (2001) 1699–1731], pointwise confidence intervals, based on likelihood ratio tests using the restricted and unrestricted MLE in the current status model, are introduced. We extend the method to the treatment of other models with monotone functions, and demonstrate our method with a new proof of the results of Banerjee–Wellner [Ann. Statist. 29 (2001) 1699–1731] and also by…

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Bayesian linear regression with sparse priors

采用稀疏先验的贝叶斯线性回归

We study full Bayesian procedures for high-dimensional linear regression under sparsity constraints. The prior is a mixture of point masses at zero and continuous distributions. Under compatibility conditions on the design matrix, the posterior distribution is shown to contract at the optimal rate for recovery of the unknown sparse vector, and to give optimal prediction of the response vector. It is also shown to select the correct sparse model, or at least the coefficients…

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Bayesian $T$-optimal discriminating designs

贝叶斯 T 最优模型判别设计

The problem of constructing Bayesian optimal discriminating designs for a class of regression models with respect to the $T$-optimality criterion introduced by Atkinson and Fedorov [Biometrika 62 (1975a) 57–70] is considered. It is demonstrated that the discretization of the integral with respect to the prior distribution leads to locally $T$-optimal discriminating design problems with a large number of model comparisons. Current methodology for the numerical construction of…

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Fused kernel-spline smoothing for repeatedly measured outcomes in a generalized partially linear model with functional single index

重复测量结果的函数单指标广义部分线性模型:核与样条融合平滑

We propose a generalized partially linear functional single index risk score model for repeatedly measured outcomes where the index itself is a function of time. We fuse the nonparametric kernel method and regression spline method, and modify the generalized estimating equation to facilitate estimation and inference. We use local smoothing kernel to estimate the unspecified coefficient functions of time, and use B-splines to estimate the unspecified function of the single…

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Asymptotic theory for density ridges

密度脊的渐近理论

The large sample theory of estimators for density modes is well understood. In this paper we consider density ridges, which are a higher-dimensional extension of modes. Modes correspond to zero-dimensional, local high-density regions in point clouds. Density ridges correspond to $s$-dimensional, local high-density regions in point clouds. We establish three main results. First we show that under appropriate regularity conditions, the local variation of the estimated ridge…

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Optimal detection of multi-sample aligned sparse signals

多样本对齐稀疏信号的最优检测

We describe, in the detection of multi-sample aligned sparse signals, the critical boundary separating detectable from nondetectable signals, and construct tests that achieve optimal detectability: penalized versions of the Berk–Jones and the higher-criticism test statistics evaluated over pooled scans, and an average likelihood ratio over the critical boundary. We show in our results an inter-play between the scale of the sequence length to signal length ratio, and the…

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Controlling the false discovery rate via knockoffs

通过 Knockoff 变量控制错误发现率

In many fields of science, we observe a response variable together with a large number of potential explanatory variables, and would like to be able to discover which variables are truly associated with the response. At the same time, we need to know that the false discovery rate (FDR)—the expected fraction of false discoveries among all discoveries—is not too high, in order to assure the scientist that most of the discoveries are indeed true and replicable. This paper…

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