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Variable Selection for Global Fréchet Regression

全局 Fréchet 回归的变量选择

Global Fréchet regression is an extension of linear regression to cover more general types of responses, such as distributions, networks, and manifolds, which are becoming more prevalent. In such models, predictors are Euclidean while responses are metric space valued. Predictor selection is of major relevance for regression modeling in the presence of multiple predictors but has not yet been addressed for Fréchet regression. Due to the metric space-valued nature of the…

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Nonparametric Estimation of Multivariate Mixtures

多元混合模型的非参数估计

A multivariate mixture model is determined by three elements: the number of components, the mixing proportions, and the component distributions. Assuming that the number of components is given and that each mixture component has independent marginal distributions, we propose a nonparametric method to estimate the component distributions. The basic idea is to convert the estimation of component density functions to a problem of estimating the coordinates of the component…

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Variable Selection in Kernel Regression Using Measurement Error Selection Likelihoods

利用测量误差选择似然进行核回归变量选择

This paper develops a nonparametric shrinkage and selection estimator via the measurement error selection likelihood approach recently proposed by Stefanski, Wu, and White. The Measurement Error Kernel Regression Operator (MEKRO) has the same form as the Nadaraya-Watson kernel estimator, but optimizes a measurement error model selection likelihood to estimate the kernel bandwidths. Much like LASSO or COSSO solution paths, MEKRO results in solution paths depending on a tuning…

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Principal weighted support vector machines for sufficient dimension reduction in binary classification

二元分类充分降维的主加权支持向量机

Sufficient dimension reduction is popular for reducing data dimensionality without stringent model assumptions. However, most existing methods may work poorly for binary classification. For example, sliced inverse regression (Li, 1991) can estimate at most one direction if the response is binary. In this paper we propose principal weighted support vector machines, a unified framework for linear and nonlinear sufficient dimension reduction in binary classification. Its…

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Local independence feature screening for nonparametric and semiparametric models by marginal empirical likelihood

基于边际经验似然的非参数与半参数模型局部独立特征筛选

We consider an independence feature screening technique for identifying explanatory variables that locally contribute to the response variable in high-dimensional regression analysis. Without requiring a specific parametric form of the underlying data model, our approach accommodates a wide spectrum of nonparametric and semiparametric model families. To detect the local contributions of explanatory variables, our approach constructs empirical likelihood locally in…

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Variable Selection for Support Vector Machines in Moderately High Dimensions

中等高维支持向量机的变量选择

Summary The support vector machine (SVM) is a powerful binary classification tool with high accuracy and great flexibility. It has achieved great success, but its performance can be seriously impaired if many redundant covariates are included. Some efforts have been devoted to studying variable selection for SVMs, but asymptotic properties, such as variable selection consistency, are largely unknown when the number of predictors diverges to ∞. We establish a unified theory…

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IsoDOT Detects Differential RNA-Isoform Expression/Usage With Respect to a Categorical or Continuous Covariate With High Sensitivity and Specificity

IsoDOT:针对分类或连续协变量的 RNA 异构体差异表达与使用检验

We have developed a statistical method named IsoDOT to assess differential isoform expression (DIE) and differential isoform usage (DIU) using RNA-seq data. Here isoform usage refers to relative isoform expression given the total expression of the corresponding gene. IsoDOT performs two tasks that cannot be accomplished by existing methods: to test DIE/DIU with respect to a continuous covariate, and to test DIE/DIU for one case versus one control. The latter task is not an…

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Automatic structure recovery for additive models

加性模型的自动结构恢复

We propose an automatic structure recovery method for additive models, based on a backfitting algorithm coupled with local polynomial smoothing, in conjunction with a new kernel-based variable selection strategy. Our method produces estimates of the set of noise predictors, the sets of predictors that contribute polynomially at different degrees up to a specified degree M, and the set of predictors that contribute beyond polynomially of degree M. We prove consistency of the…

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Homogeneity Pursuit

This paper explores the homogeneity of coefficients in high-dimensional regression, which extends the sparsity concept and is more general and suitable for many applications. Homogeneity arises when regression coefficients corresponding to neighboring geographical regions or a similar cluster of covariates are expected to be approximately the same. Sparsity corresponds to a special case of homogeneity with a large cluster of known atom zero. In this article, we propose a new…

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A Generic Path Algorithm for Regularized Statistical Estimation

正则化统计估计的通用路径算法

Regularization is widely used in statistics and machine learning to prevent overfitting and gear solution toward prior information. In general, a regularized estimation problem minimizes the sum of a loss function and a penalty term. The penalty term is usually weighted by a tuning parameter and encourages certain constraints on the parameters to be estimated. Particular choices of constraints lead to the popular lasso, fused-lasso, and other generalized ℓ1 penalized…

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Variable Selection in Nonparametric Classification Via Measurement Error Model Selection Likelihoods

基于测量误差模型选择似然的非参数分类变量选择

Using the relationships among ridge regression, LASSO estimation, and measurement error attenuation as motivation, a new measurement-error-model-based approach to variable selection is developed. After describing the approach in the familiar context of linear regression, we apply it to the problem of variable selection in nonparametric classification, resulting in a new kernel-based classifier with LASSO-like shrinkage and variable-selection properties. Finite-sample…

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Marginal empirical likelihood and sure independence feature screening

边际经验似然与确定独立特征筛选

We study a marginal empirical likelihood approach in scenarios when the number of variables grows exponentially with the sample size. The marginal empirical likelihood ratios as functions of the parameters of interest are systematically examined, and we find that the marginal empirical likelihood ratio evaluated at zero can be used to differentiate whether an explanatory variable is contributing to a response variable or not. Based on this finding, we propose a unified…

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Quantile Regression for Analyzing Heterogeneity in Ultra-High Dimension

用于分析超高维异质性的分位数回归

Ultra-high dimensional data often display heterogeneity due to either heteroscedastic variance or other forms of non-location-scale covariate effects. To accommodate heterogeneity, we advocate a more general interpretation of sparsity which assumes that only a small number of covariates influence the conditional distribution of the response variable given all candidate covariates; however, the sets of relevant covariates may differ when we consider different segments of the…

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Robust Model-Free Multiclass Probability Estimation

稳健的无模型多类别概率估计

Classical statistical approaches for multiclass probability estimation are typically based on regression techniques such as multiple logistic regression, or density estimation approaches such as linear discriminant analysis (LDA) and quadratic discriminant analysis (QDA). These methods often make certain assumptions on the form of probability functions or on the underlying distributions of subclasses. In this article, we develop a model-free procedure to estimate multiclass…

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Local quasi-likelihood with a parametric guide

带参数引导的局部拟似然

Generalized linear models and quasi-likelihood method extend the ordinary regression models to accommodate more general conditional distributions of the response. Nonparametric methods need no explicit parametric specification and the resulting model is completely determined by the data themselves. However nonparametric estimation schemes generally have a slower convergence rate such as the local polynomial smoothing estimation of nonparametric generalized linear models…

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Semiparametric Estimation of Covariance Matrixes for Longitudinal Data

纵向数据协方差矩阵的半参数估计

Estimation of longitudinal data covariance structure poses significant challenges because the data are usually collected at irregular time points. A viable semiparametric model for covariance matrices was proposed in Fan, Huang and Li (2007) that allows one to estimate the variance function nonparametrically and to estimate the correlation function parametrically via aggregating information from irregular and sparse data points within each subject. However, the asymptotic…

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