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Weighted residual empirical processes, martingale transformations, and model specification tests for regressions with diverging number of parameters

参数维度增长下的加权残差经验过程、鞅变换与回归设定检验

This paper explores hypothesis testing for the parametric forms of the mean and variance functions in regression models under diverging-dimension settings. To mitigate the curse of dimensionality, we introduce weighted residual empirical process-based tests, both with and without martingale transformations. The asymptotic properties of these tests are derived from the behavior of weighted residual empirical processes and their martingale transformations under the null and…

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Statistical Inference for High-Dimensional Convoluted Rank Regression

高维卷积秩回归的统计推断

High-dimensional penalized rank regression is a powerful tool for modeling high-dimensional data due to its robustness and estimation efficiency. However, the non-smoothness of the rank loss brings great challenges to the computation. To solve this critical issue, high-dimensional convoluted rank regression has been recently proposed, introducing penalized convoluted rank regression estimators. However, these developed estimators cannot be directly used to make inference. In…

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Test and Measure for Partial Mean Dependence Based on Machine Learning Methods

基于机器学习的部分均值依赖检验与度量

It is of importance to investigate the significance of a subset of covariates W for the response Y given covariates Z in regression modeling. To this end, we propose a significance test for the partial mean independence problem based on machine learning methods and data splitting. The test statistic converges to the standard Chi-squared distribution under the null hypothesis while it converges to a normal distribution under the fixed alternative hypothesis. Power enhancement…

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Model-Free Statistical Inference on High-Dimensional Data

高维数据的无模型统计推断

This article aims to develop an effective model-free inference procedure for high-dimensional data. We first reformulate the hypothesis testing problem via sufficient dimension reduction framework. With the aid of new reformulation, we propose a new test statistic and show that its asymptotic distribution is χ2 distribution whose degree of freedom does not depend on the unknown population distribution. We further conduct power analysis under local alternative hypotheses. In…

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Reprint: Statistical inference for linear mediation models with high-dimensional mediators and application to studying stock reaction to COVID-19 pandemic

重印:高维线性中介模型推断及新冠疫情股票反应应用

Mediation analysis draws increasing attention in many research areas such as economics, finance and social sciences. In this paper, we propose new statistical inference procedures for high dimensional mediation models, in which both the outcome model and the mediator model are linear with high dimensional mediators. Traditional procedures for mediation analysis cannot be used to make statistical inference for high dimensional linear mediation models due to…

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Estimations and Tests for Generalized Mediation Models with High-Dimensional Potential Mediators

高维潜在中介变量下广义中介模型的估计与检验

Motivated by an empirical analysis of stock reaction to COVID-19 pandemic, we propose a generalized mediation model with high-dimensional potential mediators to study the mediation effects of financial metrics that bridge company’s sector and stock value. We propose an estimation procedure for the direct effect via a partial penalized maximum likelihood method and establish its theoretical properties. We develop a Wald test for the indirect effect and show that the proposed…

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Threshold Selection in Feature Screening for Error Rate Control

控制错误率的特征筛选阈值选择

Hard thresholding rule is commonly adopted in feature screening procedures to screen out unimportant predictors for ultrahigh-dimensional data. However, different thresholds are required to adapt to different contexts of screening problems and an appropriate thresholding magnitude usually varies from the model and error distribution. With an ad-hoc choice, it is unclear whether all of the important predictors are selected or not, and it is very likely that the procedures…

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Statistical inference for linear mediation models with high-dimensional mediators and application to studying stock reaction to COVID-19 pandemic

高维线性中介模型的统计推断及疫情股票反应应用

Mediation analysis draws increasing attention in many research areas such as economics, finance and social sciences. In this paper, we propose new statistical inference procedures for high dimensional mediation models, in which both the outcome model and the mediator model are linear with high dimensional mediators. Traditional procedures for mediation analysis cannot be used to make statistical inference for high dimensional linear mediation models due to…

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False Discovery Rate Control Under General Dependence By Symmetrized Data Aggregation

通过对称化数据聚合控制一般依赖下的错误发现率

We develop a new class of distribution-free multiple testing rules for false discovery rate (FDR) control under general dependence. A key element in our proposal is a symmetrized data aggregation (SDA) approach to incorporating the dependence structure via sample splitting, data screening, and information pooling. The proposed SDA filter first constructs a sequence of ranking statistics that fulfill global symmetry properties, and then chooses a data-driven threshold along…

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High-Dimensional Mediation Analysis for Selecting DNA Methylation Loci Mediating Childhood Trauma and Cortisol Stress Reactivity

高维中介分析:筛选连接童年创伤与皮质醇应激反应的 DNA 甲基化位点

Childhood trauma tends to influence cortisol stress reactivity through the mediating effects of DNA methylation. Houtepen et al. conducted a study to investigate the role of DNA methylation in cortisol stress reactivity and its relationship with childhood trauma. The study collected a dataset consisting of 385,882 DNA methylation loci, cortisol stress reactivity, one-dimensional score on a childhood trauma questionnaire and several covariates for 85 healthy individuals. Of…

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Niwen Zhou and Xu Guo’s Contribution to the Discussion of ‘Assumption-Lean Inference for Generalised Linear Model Parameters’ by Vansteelandt and Dukes

周倪文与郭旭对《广义线性模型参数的少假设推断》的讨论

We thank Professors Vansteelandt and Dukes for their innovative and stimulating paper. They introduce a new estimand which reduces to the exposure effect parameter when the (semi)parametric model holds, is generic for continuous or discrete exposure, and still captures conditional association when model assumption fails. We make some additional understanding of the new estimand and introduce a related new estimand. Here we consider the expectation of the ratio. Here β· and…

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Model Checking for Parametric Single-index Models: A Dimension Reduction Model-Adaptive Approach

参数单指标模型检验:降维模型自适应方法

Summary Local smoothing testing based on multivariate non-parametric regression estimation is one of the main model checking methodologies in the literature. However, the relevant tests suffer from the typical curse of dimensionality, resulting in slow rates of convergence to their limits under the null hypothesis and less deviation from the null hypothesis under alternative hypotheses. This problem prevents tests from maintaining the level of significance well and makes…

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