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Enhanced Inference for Distributions and Quantiles of Individual Treatment Effects in Various Experiments

不同实验中个体处理效应分布与分位数的增强推断

Understanding treatment effect heterogeneity has become increasingly important in many fields. In this paper we study distributions and quantiles of individual treatment effects to provide a more comprehensive and robust understanding of treatment effects beyond usual averages, despite they are more challenging to infer due to nonidentifiability from the observed data. Recent randomization-based approaches offer finite-sample valid inference for treatment effect…

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Sensitivity analysis for observational studies with flexible matched designs

灵活匹配设计下观察性研究的敏感性分析

Abstract Observational studies provide invaluable opportunities to draw causal inference, but they may suffer from biases due to pretreatment differences between treated and control units. Matching is a popular approach to reduce observed covariate imbalance. To tackle unmeasured confounding, a sensitivity analysis is often conducted to investigate how robust a causal conclusion is to the strength of unmeasured confounding. For matched observational studies, Rosenbaum…

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Asymptotic theory of the best-choice rerandomization using the Mahalanobis distance

基于马氏距离的最优选择再随机化渐近理论

Rerandomization, a design that utilizes pretreatment covariates and improves their balance between different treatment groups, has received attention recently in both theory and practice. From a survey by Bruhn and McKenzie (2009), there are at least two types of rerandomization that are used in practice: the first rerandomizes the treatment assignment until covariate imbalance is below a prespecified threshold; the second randomizes the treatment assignment multiple times…

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Sensitivity Analysis for Quantiles of Hidden Biases in Matched Observational Studies

匹配观察研究中隐蔽偏差分位数的敏感性分析

Causal conclusions from observational studies may be sensitive to unmeasured confounding. In such cases, a sensitivity analysis is often conducted, which tries to infer the minimum amount of hidden biases or the minimum strength of unmeasured confounding needed in order to explain away the observed association between treatment and outcome. If the needed bias is large, then the treatment is likely to have significant effects. The Rosenbaum sensitivity analysis is a modern…

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Randomization-based Z -estimation for evaluating average and individual treatment effects

评估平均与个体处理效应的随机化 Z 估计

Summary Randomized experiments have been the gold standard for drawing causal inference. The conventional model-based approach has been one of the most popular methods of analysing treatment effects from randomized experiments, which is often carried out through inference for certain model parameters. In this paper, we provide a systematic investigation of model-based analyses for treatment effects under the randomization-based inference framework. This framework does not…

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Treatment effect quantiles in stratified randomized experiments and matched observational studies

分层随机实验与匹配观察研究中的个体处理效应分位数

Summary Evaluating the treatment effect has become an important topic for many applications. However, most existing literature focuses mainly on average treatment effects. When the individual effects are heavy tailed or have outlier values, not only may the average effect not be appropriate for summarizing treatment effects, but also the conventional inference for it can be sensitive and possibly invalid due to poor large-sample approximations. In this paper we focus on…

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Power and sample size calculations for rerandomization

再随机化设计的检验功效与样本量计算

Summary Power analyses are an important aspect of experimental design, because they help determine how experiments are implemented in practice. It is common to specify a desired level of power and compute the sample size necessary to obtain that power. Such calculations are well known for completely randomized experiments, but there can be many benefits to using other experimental designs. For example, it has recently been established that rerandomization, where subjects are…

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Randomisation inference beyond the sharp null: bounded null hypotheses and quantiles of individual treatment effects

超越尖锐零假设的随机化推断:有界零假设与个体处理效应分位数

Abstract Randomisation inference (RI) is typically interpreted as testing Fisher’s ‘sharp’ null hypothesis that all unit-level effects are exactly zero. This hypothesis is often criticised as restrictive and implausible, making its rejection scientifically uninteresting. We show, however, that many randomisation tests are also valid for a ‘bounded’ null hypothesis under which the unit-level effects are all non-positive (or all non-negative) but are otherwise heterogeneous.…

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Rejective Sampling, Rerandomization, and Regression Adjustment in Survey Experiments

调查实验中的拒绝式抽样、再随机化与回归调整

Classical randomized experiments, equipped with randomization-based inference, provide assumption-free inference for treatment effects. They have been the gold standard for drawing causal inference and provide excellent internal validity. However, they have also been criticized for questionable external validity, in the sense that the conclusion may not generalize well to a larger population. The randomized survey experiment is a design tool that can help mitigate this…

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Rerandomization with diminishing covariate imbalance and diverging number of covariates

协变量不平衡递减且协变量数量增长时的再随机化

Completely randomized experiments have been the gold standard for drawing causal inference because they can balance all potential confounding on average. However, they may suffer from unbalanced covariates for realized treatment assignments. Rerandomization, a design that rerandomizes the treatment assignment until a prespecified covariate balance criterion is met, has recently got attention due to its easy implementation, improved covariate balance and more efficient…

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Rerandomization and Regression Adjustment

再随机化与回归调整

Summary Randomization is a basis for the statistical inference of treatment effects without strong assumptions on the outcome-generating process. Appropriately using covariates further yields more precise estimators in randomized experiments. R. A. Fisher suggested blocking on discrete covariates in the design stage or conducting analysis of covariance in the analysis stage. We can embed blocking in a wider class of experimental design called rerandomization, and extend the…

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Rerandomization in $2^{K}$ factorial experiments

二水平多因子实验中的重随机化

With many pretreatment covariates and treatment factors, the classical factorial experiment often fails to balance covariates across multiple factorial effects simultaneously. Therefore, it is intuitive to restrict the randomization of the treatment factors to satisfy certain covariate balance criteria, possibly conforming to the tiers of factorial effects and covariates based on their relative importances. This is rerandomization in factorial experiments. We study the…

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Randomization Inference for Peer Effects

同伴效应的随机化推断

Xinran Lia, Peng Dingb*, Qian Linc, Dawei Yangd & Jun S. Liuaa Department of Statistics, Harvard University, Cambridge, MA; b Department of Statistics, University of California, Berkeley, CA; c Center for Statistical Science, Department of Industrial Engineering, Tsinghua University, Beijing, P. R. China; d Bureau of Personnel of Chinese Academy of Sciences & School of Education of Peking University, Beijing, P. R. ChinaSupplementary materials for this article are available…

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General Forms of Finite Population Central Limit Theorems with Applications to Causal Inference

有限总体中心极限定理的一般形式及其因果推断应用

Frequentists’ inference often delivers point estimators associated with confidence intervals or sets for parameters of interest. Constructing the confidence intervals or sets requires understanding the sampling distributions of the point estimators, which, in many but not all cases, are related to asymptotic Normal distributions ensured by central limit theorems. Although previous literature has established various forms of central limit theorems for statistical inference in…

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