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公平性感知的高斯图回归及脑共表达QTL研究应用AI 解读

Glioblastoma multiforme (GBM) is a highly aggressive brain cancer with largely ineffective treatment. It is imperative to explore more effective therapies, such as gene-based treatments. For co-expression QTL studies of GBM, we develop fairness-aware Gaussian graphical regression models (Fair RegGGMs), which can determine how genetic variants modulate subject-level gene networks, and recover both population-level and subject-level gene graphs, while ensuring that the…

不完整数据下分位数估计的一般框架AI 解读

Summary Quantile estimation has attracted significant research interest in recent years. However, there has been only a limited literature on quantile estimation in the presence of incomplete data. We propose a general framework to address this problem. Our framework combines the two widely adopted approaches for missing data analysis, the imputation approach and the inverse probability weighting approach, via the empirical likelihood method. The method proposed is capable…