Interim analyses using repeated confidence bands
使用重复置信带的中期分析
Clinical trials often include interim analyses that compare treatment groups with respect to the mean function of a response process. Sometimes it is unclear how the mean functions of the groups might differ, and thus one cannot confidently prespecify a simple metric upon which a stopping rule or repeated confidence interval can be based. This motivated us to extend the repeated confidence intervals approach for a finite-dimensional parameter (Jennison & Turnbull, 1989) to…