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基于分位数函数的分布型结局回归及心率与活动量应用AI 解读

Modern clinical and epidemiological studies widely employ wearables to record parallel streams of real-time data on human physiology and behavior. With recent advances in distributional data analysis, these high-frequency data are now often treated as distributional observations resulting in novel regression settings. Motivated by these modeling setups, we develop a distributional outcome regression via quantile functions (DORQF) that expands existing literature with three…

多层矩阵变量分析及其在临床人群加速度计活动测量中的应用AI 解读

The number of studies where the primary measurement is a matrix is exploding. In response to this, we propose a statistical framework for modeling populations of repeatedly observed matrix-variate measurements. The 2D structure is handled via a matrix-variate distribution with decomposable row/column-specific covariance matrices and a linear mixed effect framework is used to model the multilevel design. The proposed framework flexibly expands to accommodate many common…

百万维以上数据的快速精确 Bootstrap 主成分分析AI 解读

Many have suggested a bootstrap procedure for estimating the sampling variability of principal component analysis (PCA) results. However, when the number of measurements per subject (p) is much larger than the number of subjects (n), calculating and storing the leading principal components (PCs) from each bootstrap sample can be computationally infeasible. To address this, we outline methods for fast, exact calculation of bootstrap PCs, eigenvalues, and scores. Our methods…