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通过协变量调整消除因果目标选择偏差的共同原因原则AI 解读

Average treatment effects (ATEs) may be subject to selection bias when they are estimated among only a nonrepresentative subset of the target population. Selection bias can sometimes be eliminated by conditioning on a “sufficient adjustment set” of covariates, even for some forms of missingness not at random (MNAR). Without requiring full specification of the causal structure, we consider sufficient adjustment sets to allow nonparametric identification of conditional ATEs in…

拒绝潜在因子模型结构解释的统计检验AI 解读

Abstract Factor analysis is often used to assess whether a single univariate latent variable is sufficient to explain most of the covariance among a set of indicators for some underlying construct. When evidence suggests that a single factor is adequate, research often proceeds by using a univariate summary of the indicators in subsequent research. Implicit in such practices is the assumption that it is the underlying latent, rather than the indicators, that is causally…

元分析中未测量混杂的敏感性分析AI 解读

Random-effects meta-analyses of observational studies can produce biased estimates if the synthesized studies are subject to unmeasured confounding. We propose sensitivity analyses quantifying the extent to which unmeasured confounding of specified magnitude could reduce to below a certain threshold the proportion of true effect sizes that are scientifically meaningful. We also develop converse methods to estimate the strength of confounding capable of reducing the…

未测中介—结局混杂下中介效应的锐敏感性界限AI 解读

It is often of interest to decompose the total effect of an exposure into a component that acts on the outcome through some mediator and a component that acts independently through other pathways. Said another way, we are interested in the direct and indirect effects of the exposure on the outcome. Even if the exposure is randomly assigned, it is often infeasible to randomize the mediator, leaving the mediator-outcome confounding not fully controlled. We develop a…

聚类鼓励设计中因果机制的识别与估计：用贝叶斯主分层分解蚊帐干预效应AI 解读

Exploration of causal mechanisms is often important for researchers and policymakers to understand how an intervention works and how it can be improved. This task can be crucial in clustered encouragement designs (CED). Encouragement design studies arise frequently when the treatment cannot be enforced because of ethical or practical constrains and an encouragement intervention (information campaigns, incentives, etc) is conceived with the purpose of increasing the uptake of…

混杂变量的定义AI 解读

The causal inference literature has provided a clear formal definition of confounding expressed in terms of counterfactual independence. The literature has not, however, come to any consensus on a formal definition of a confounder, as it has given priority to the concept of confounding over that of a confounder. We consider a number of candidate definitions arising from various more informal statements made in the literature. We consider the properties satisfied by each…

暴露误分类下的加性交互作用推断AI 解读

Results are given concerning inferences that can be drawn about interaction when binary exposures are subject to certain forms of independent nondifferential misclassification. Tests for interaction, using the misclassified exposures, are valid provided the probability of misclassification satisfies certain bounds. Results are given for additive statistical interactions, for causal interactions corresponding to synergism in the sufficient cause framework and for so-called…

充分原因交互作用的半参数检验AI 解读

Summary A sufficient cause interaction between two exposures signals the presence of individuals for whom the outcome would occur only under certain values of the two exposures. When the outcome is dichotomous and all exposures are categorical, then, under certain no confounding assumptions, empirical conditions for sufficient cause interactions can be constructed on the basis of the sign of linear contrasts of conditional outcome probabilities between differently exposed…

用于因果推断的带符号有向无环图AI 解读

Summary Formal rules governing signed edges on causal directed acyclic graphs are described and it is shown how these rules can be useful in reasoning about causality. Specifically, the notions of a monotonic effect, a weak monotonic effect and a signed edge are introduced. Results are developed relating these monotonic effects and signed edges to the sign of the causal effect of an intervention in the presence of intermediate variables. The incorporation of signed edges in…