Comparison of Longitudinal Trajectories Using a High-Dimensional Partial Linear Semiparametric Mixed-Effects Model
利用高维部分线性半参数混合效应模型比较纵向轨迹
In longitudinal research, it is essential to compare sets of trajectories, commonly seen as changes over time in different treatment or patient groups. This paper presents a partial linear semiparametric mixed-effects model (PLSMM) for the analysis and comparison of nonlinear longitudinal trajectories with high-dimensional covariates across groups. Our flexible modeling framework can effectively handle complex temporal effects and extensive data while providing statistical…