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Nested Markov properties for acyclic directed mixed graphs

无环有向混合图的嵌套马尔可夫性质

Conditional independence models associated with directed acyclic graphs (DAGs) may be characterized in at least three different ways: via a factorization, the global Markov property (given by the d-separation criterion), and the local Markov property. Marginals of DAG models also imply equality constraints that are not conditional independences; the well-known “Verma constraint” is an example. Constraints of this type are used for testing edges, and in a computationally…

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Thomas S. Richardson’s Contribution to the Discussion of ‘Assumption-Lean Inference for Generalised Linear Model Parameters’ by Vansteelandt and Dukes

Richardson 对《广义线性模型参数的弱假设推断》的讨论

I congratulate the authors on an interesting and thought provoking contribution to the literature on modelling associations. A particular strength of the approach advocated by the authors is that it may facilitate the estimation of main effects on the relative risk scale, by taking g = log. In contrast, a GLM specification such as (4) with log link presents difficulties owing to the variation dependence between β and ω(·). This dependence, also called non-congeniality, often…

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Partial Identification of the Average Treatment Effect Using Instrumental Variables: Review of Methods for Binary Instruments, Treatments, and Outcomes

工具变量下平均处理效应的部分识别:二元工具、处理与结果的方法综述

Several methods have been proposed for partially or point identifying the average treatment effect (ATE) using instrumental variable (IV) type assumptions. The descriptions of these methods are widespread across the statistical, economic, epidemiologic, and computer science literature, and the connections between the methods have not been readily apparent. In the setting of a binary instrument, treatment, and outcome, we review proposed methods for partial and point…

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Identification and estimation of causal effects with outcomes truncated by death

死亡截断结局下因果效应的识别与估计

It is common in medical studies that the outcome of interest is truncated by death, meaning that a subject has died before the outcome could be measured. In this case, restricted analysis among survivors may be subject to selection bias. Hence, it is of interest to estimate the survivor average causal effect, defined as the average causal effect among the subgroup consisting of subjects who would survive under either exposure. In this paper, we consider the identification…

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Causal Analysis of Ordinal Treatments and Binary Outcomes Under Truncation by Death

死亡截断下有序处理与二元结局的因果分析

Summary It is common that, in multiarm randomized trials, the outcome of interest is ‘truncated by death’, meaning that it is only observed or well-defined conditioning on an intermediate outcome. In this case, in addition to pairwise contrasts, the joint inference for all treatment arms is also of interest. Under a monotonicity assumption we present methods for both pairwise and joint causal analyses of ordinal treatments and binary outcomes in the presence of truncation by…

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Estimating the effect of joint interventions from observational data in sparse high-dimensional settings

稀疏高维环境下从观测数据估计联合干预效应

We consider the estimation of joint causal effects from observational data. In particular, we propose new methods to estimate the effect of multiple simultaneous interventions (e.g., multiple gene knockouts), under the assumption that the observational data come from an unknown linear structural equation model with independent errors. We derive asymptotic variances of our estimators when the underlying causal structure is partly known, as well as high-dimensional consistency…

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On falsification of the binary instrumental variable model

Instrumental variables are widely used for estimating causal effects in the presence of unmeasured confounding. The discrete instrumental variable model has testable implications for the law of the observed data. However, current assessments of instrumental validity are typically based solely on subject-matter arguments rather than these testable implications, partly due to a lack of formal statistical tests with known properties. In this paper, we develop simple procedures…

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Markovian acyclic directed mixed graphs for discrete data

离散数据的马尔可夫无环有向混合图

Acyclic directed mixed graphs (ADMGs) are graphs that contain directed ($\rightarrow$) and bidirected ($\leftrightarrow$) edges, subject to the constraint that there are no cycles of directed edges. Such graphs may be used to represent the conditional independence structure induced by a DAG model containing hidden variables on its observed margin. The Markovian model associated with an ADMG is simply the set of distributions obeying the global Markov property, given via a…

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Marginal Log-Linear Parameters for Graphical Markov Models

图形马尔可夫模型的边际对数线性参数

Summary Marginal log-linear (MLL) models provide a flexible approach to multivariate discrete data. MLL parameterizations under linear constraints induce a wide variety of models, including models that are defined by conditional independences. We introduce a subclass of MLL models which correspond to acyclic directed mixed graphs under the usual global Markov property. We characterize for precisely which graphs the resulting parameterization is variation independent. The MLL…

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Learning high-dimensional directed acyclic graphs with latent and selection variables

存在潜在变量与选择变量时的高维有向无环图学习

We consider the problem of learning causal information between random variables in directed acyclic graphs (DAGs) when allowing arbitrarily many latent and selection variables. The FCI (Fast Causal Inference) algorithm has been explicitly designed to infer conditional independence and causal information in such settings. However, FCI is computationally infeasible for large graphs. We therefore propose the new RFCI algorithm, which is much faster than FCI. In some situations…

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Resolving Contested Elections: The Limited Power of Post-Vote Vote-Choice Data

解决选举争议:投票后投票选择数据的有限检验功效

In close elections, the losing side has an incentive to obtain evidence that the election result is incorrect. Sometimes this evidence comes in the form of court testimony from a sample of invalid voters, and this testimony is used to adjust vote totals (Borders v King County, 2005; Belcher v Mayor of Ann Arbor, 1978). However, while courts may be reluctant to make explicit findings about out-of-sample data (e.g. invalid voters that do not testify), when samples are used to…

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Binary Models for Marginal Independence

边际独立性的二元变量模型

Summary Log-linear models are a classical tool for the analysis of contingency tables. In particular, the subclass of graphical log-linear models provides a general framework for modelling conditional independences. However, with the exception of special structures, marginal independence hypotheses cannot be accommodated by these traditional models. Focusing on binary variables, we present a model class that provides a framework for modelling marginal independences in…

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Chain Graph Models and their Causal Interpretations

链图模型及其因果解释

Summary Chain graphs are a natural generalization of directed acyclic graphs and undirected graphs. However, the apparent simplicity of chain graphs belies the subtlety of the conditional independence hypotheses that they represent. There are many simple and apparently plausible, but ultimately fallacious, interpretations of chain graphs that are often invoked, implicitly or explicitly. These interpretations also lead to flawed methods for applying background knowledge to…

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