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Gaussianized design optimization for covariate balance in randomized experiments

随机实验中协变量平衡的高斯化设计优化

Abstract Achieving covariate balance in randomized experiments enhances the precision of treatment effect estimation. However, existing methods often require heuristic adjustments based on domain knowledge and are primarily developed for binary treatments. This paper presents Gaussianized Design Optimization, a novel framework for optimally balancing covariates in experimental design. The core idea is to Gaussianize the treatment assignments: we model treatments as…

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Randomization inference when N equals one

样本单位数为一时的随机化推断

Summary For decades, $ N $-of-1 experiments, where a unit serves as its own control and treatment in different time windows, have been used in certain medical contexts. However, due to effects that accumulate over long time windows and interventions that have complex evolution, a lack of robust inference tools has limited the widespread applicability of such $ N $-of-1 designs. This work combines techniques from experimental design in causal inference and system…

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Detecting Weak Distribution Shifts via Displacement Interpolation

利用位移插值检测微弱分布变化

Detecting weak, systematic distribution shifts and quantitatively modeling individual, heterogeneous responses to policies or incentives have found increasing empirical applications in social and economic sciences. Given two probability distributions P (null) and Q (alternative), we study the problem of detecting weak distribution shift deviating from the null P toward the alternative Q, where the level of deviation vanishes as a function of n, the sample size. We propose a…

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Deep Neural Networks for Estimation and Inference

用于估计与推断的深度神经网络

We study deep neural networks and their use in semiparametric inference. We establish novel nonasymptotic high probability bounds for deep feedforward neural nets. These deliver rates of convergence that are sufficiently fast (in some cases minimax optimal) to allow us to establish valid second‐step inference after first‐step estimation with deep learning, a result also new to the literature. Our nonasymptotic high probability bounds, and the subsequent semiparametric…

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