Kernel and Probit Estimates in Quantal Bioassay
二元反应生物测定中的核估计与 Probit 估计
A kernel method for the estimation of quantal dose-response curves is considered. In contrast to parametric modeling, this local smoothing method does not require any assumptions beyond smoothness of the dose-response curve and, in this sense, is nonparametric. In finite-sample situations, the kernel estimate of the dose-response curve is not necessarily monotone and, therefore, if the additional assumption of monotonicity of the dose-response curve is made, a monotonized…