The Phylogenetic Kantorovich–Rubinstein Metric for Environmental Sequence Samples
环境序列样本的系统发育 Kantorovich–Rubinstein 距离
Summary It is now common to survey microbial communities by sequencing nucleic acid material extracted in bulk from a given environment. Comparative methods are needed that indicate the extent to which two communities differ given data sets of this type. UniFrac, which gives a somewhat ad hoc phylogenetics-based distance between two communities, is one of the most commonly used tools for these analyses. We provide a foundation for such methods by establishing that, if we…