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破坏性寿命试验的有效序贯设计及动物分批处死实验应用AI 解读

We consider the scheduling of inspection times in a life testing experiment when testing is destructive. One application is to animal carcinogenicity tests where it is desired to find serial sacrifice schedules which allow efficient estimation of the onset time distribution for a tumour which is assumed irreversible, nonlethal and occult, i.e. detectable only at death. A class of designs are introduced and their properties are discussed. It is shown how to construct a design…

破坏性寿命试验的高效序贯设计及动物分批处死实验应用AI 解读

We consider the scheduling of inspection times in a life testing experiment when testing is destructive. One application is to animal carcinogenicity tests where it is desired to find serial sacrifice schedules which allow efficient estimation of the onset time distribution for a tumour which is assumed irreversible, nonlethal and occult, i.e. detectable only at death. A class of designs are introduced and their properties are discussed. It is shown how to construct a design…