Latent Variable Model for Joint Analysis of Multiple Repeated Measures and Bivariate Event Times
多项重复测量与双变量事件时间联合分析的潜变量模型
This article presents a novel approach to analyzing a complex dataset from a prevention trial, where outcomes comprise multiple repeated mental health items and times to initiation of alcohol and tobacco use. The dataset has a nonnegligible portion of missing values and interval or left censored events. The substantive interest of the trial suggests a psychiatric distress latent variable that is reflected in the mental health items and potentially affects initiation of…