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Smooth quantile ratio estimation

平滑分位数比估计

We propose a novel approach to estimating the mean difference between two highly skewed distributions. The method, which we call smooth quantile ratio estimation, smooths, over percentiles, the ratio of the quantiles of the two distributions. The method defines a large class of estimators, including the sample mean difference, the maximum likelihood estimator under log-normal samples and the L-estimator. We derive asymptotic properties such as consistency and asymptotic…

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Lorelogram: A Regression Approach to Exploring Dependence in Longitudinal Categorical Responses

Lorelogram:探索纵向分类响应依赖性的回归方法

We propose flexible regression estimators of the marginal pairwise log-odds ratio measure of association for longitudinal categorical responses. The function that we estimate is the log-odds ratio analog of the correlogram; hence we name the function the lorelogram. Measuring the association of categorical responses on the log-odds scale allows ease of interpretation and allows pairwise association to remain unconstrained by the marginal means, a feature not shared by…

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Latent Variable Regression for Multiple Discrete Outcomes

多重离散结果的潜变量回归

Quantifying human health and functioning poses significant challenges in many research areas. Commonly in the social and behavioral sciences and increasingly in epidemiologic research, multiple indicators are utilized as responses in lieu of an obvious single measure for an outcome of interest. In this article we study the concomitant latent class model for analyzing such multivariate categorical outcome data. We develop practical theory for reducing and identifying such…

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Marginal Regression Models for Clustered Ordinal Measurements

聚类有序测量的边际回归模型

This article constructs statistical models for clustered ordinal measurements. We specify two regression models: one for the marginal means and one for the marginal pairwise global odds ratios. Of particular interest are problems in which the odds ratio regression is a focus. Simple assumptions about higher-order conditional moments give a quadratic exponential likelihood function with second-order estimating equations (GEE2) as score equations. But computational difficulty…

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Multivariate Regression Analyses for Categorical Data

分类数据的多元回归分析

SUMMARY It is common to observe a vector of discrete and/or continuous responses in scientific problems where the objective is to characterize the dependence of each response on explanatory variables and to account for the association between the outcomes. The response vector can comprise repeated observations on one variable, as in longitudinal studies or genetic studies of families, or can include observations for different variables. This paper discusses a class of models…

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Longitudinal data analysis using generalized linear models

使用广义线性模型分析纵向数据

This paper proposes an extension of generalized linear models to the analysis of longitudinal data. We introduce a class of estimating equations that give consistent estimates of the regression parameters and of their variance under mild assumptions about the time dependence. The estimating equations are derived without specifying the joint distribution of a subject's observations yet they reduce to the score equations for niultivariate Gaussian outcomes. Asymptotic theory…

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The analysis of binary longitudinal data with time independent covariates

具有时间不变协变量的二元纵向数据分析

This paper considers extensions of logistic regression to the case where the binary outcome variable is observed repeatedly for each subject. We propose two working models that lead to consistent estimates of the regression parameters and of their variances under mild assumptions about the time dependence within each subject's data. The efficiency of the proposed estimators is examined. An analysis of stress in mothers with infants is presented to illustrate the proposed…

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