A serially correlated gamma frailty model for longitudinal count data
纵向计数数据的序列相关伽马脆弱性模型
A Poisson‐gamma model is introduced to account for between‐subjects heterogeneity and within‐subjects serial correlation occurring in longitudinal count data. The model extends the usual time‐constant shared frailty approach to allow time‐varying serially correlated gamma frailty whilst retaining standard marginal assumptions. A composite likelihood approach to estimation and testing for serial correlation is proposed. The work is motivated by a clinical trial on…