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Propensity scores in the design of observational studies for causal effects

倾向得分在观察性因果研究设计中的作用

Summary The design of any study, whether experimental or observational, that is intended to estimate the causal effects of a treatment condition relative to a control condition refers to those activities that precede any examination of outcome variables. As defined in our 1983 article (Rosenbaum & Rubin, 1983), the propensity score is the unit-level conditional probability of assignment to treatment versus control given the observed covariates; so the propensity score…

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A conditional test with demonstrated insensitivity to unmeasured bias in matched observational studies

匹配观察研究中对未测偏倚不敏感的条件检验

Summary In an observational study matched for observed covariates, an association between treatment received and outcome exhibited may indicate not an effect caused by the treatment, but merely some bias in the allocation of treatments to individuals within matched pairs. The evidence that distinguishes moderate biases from causal effects is unevenly dispersed among possible comparisons in an observational study: some comparisons are insensitive to larger biases than others.…

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