A Signal Extraction Approach to Modeling Hormone Time Series with Pulses and a Changing Baseline
用信号提取方法建模具有脉冲与变化基线的激素时间序列
Hormones serve as regulating signals for many biological processes. In recent years, it was determined that many hormones are secreted in a pulsatile manner and that the pulsatile secretion pattern, in addition to the absolute concentration level, is important in regulating biological processes. Consequently, it is necessary to characterize the latent secretion patterns from measurements of concentration levels. The characterization is complicated by the presence of a…