Estimation of Direct Effects for Survival Data by using the Aalen Additive Hazards Model
使用Aalen加性风险模型估计生存数据的直接效应
Summary We extend the definition of the controlled direct effect of a point exposure on a survival outcome, other than through some given, time-fixed intermediate variable, to the additive hazard scale. We propose two-stage estimators for this effect when the exposure is dichotomous and randomly assigned and when the association between the intermediate variable and the survival outcome is confounded only by measured factors, which may themselves be affected by the exposure.…