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Estimation from cross-sectional samples under bias and dependence

偏差与依赖并存时的横截面样本估计

A population can be entered at a known sequence of discrete times; it is sampled cross-sectionally, and the sojourn times of individuals in the sample are observed. It is well known that cross-sectioning leads to length-bias, but less well known and often ignored that it may also result in dependence among the observations. We show that observed sojourn times are independent only under a multinomial entrance process. We study asymptotic properties of parametric and…

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Optimal allocation to maximize the power of two-sample tests for binary response

最大化二元响应两样本检验功效的最优分配

We study allocations that maximize the power of tests of equality of two treatments having binary outcomes. When a normal approximation applies, the asymptotic power is maximized by minimizing the variance, leading to a Neyman allocation that assigns observations in proportion to the standard deviations. This allocation, which in general requires knowledge of the parameters of the problem, is recommended in a large body of literature. Under contiguous alternatives the normal…

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Nonparametric estimation of the probability of illness in the illness-death model under cross-sectional sampling

横截面抽样下疾病—死亡模型患病概率的非参数估计

Cross-sectional sampling is an attractive design that saves resources but results in biased data. For proper inference, one should first discover the bias function and then weigh observations appropriately. We consider cross-sectioning of the illness-death model with the aim of estimating the probability of visiting the illness state before death. We develop simple consistent and asymptotically normal estimators under various assumptions on the model and data collection and,…

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