Information-regret compromise in covariate-adaptive treatment allocation
协变量自适应治疗分配中的信息与遗憾权衡
Covariate-adaptive treatment allocation is considered in the situation when a compromise must be made between information (about the dependency of the probability of success of each treatment upon influential covariates) and cost (in terms of number of subjects receiving the poorest treatment). Information is measured through a design criterion for parameter estimation, the cost is additive and is related to the success probabilities. Within the framework of approximate…