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Off-Policy Evaluation in Doubly Inhomogeneous Environments

双重非同质环境中的离策略评估

This work aims to study off-policy evaluation (OPE) under scenarios where two key reinforcement learning (RL) assumptions -- temporal stationarity and individual homogeneity are both violated. To handle the ``double inhomogeneities", we propose a class of latent factor models for the reward and observation transition functions, under which we develop a general OPE framework that consists of both model-based and model-free approaches. To our knowledge, this is the first paper…

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A nonparametric doubly robust test for a continuous treatment effect

连续处理效应的非参数双重稳健检验

The vast majority of literature on evaluating the significance of a treatment effect based on observational data has been confined to discrete treatments. These methods are not applicable to drawing inference for a continuous treatment, which arises in many important applications. To adjust for confounders when evaluating a continuous treatment, existing inference methods often rely on discretizing the treatment or using (possibly misspecified) parametric models for the…

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ANALYSIS OF GLOBAL AND LOCAL OPTIMA OF REGULARIZED QUANTILE REGRESSION IN HIGH DIMENSIONS: A SUBGRADIENT APPROACH

高维正则化分位数回归全局与局部最优解的次梯度分析

Regularized quantile regression (QR) is a useful technique for analyzing heterogeneous data under potentially heavy-tailed error contamination in high dimensions. This paper provides a new analysis of the estimation/prediction error bounds of the global solution of $L_1$ -regularized QR (QR-LASSO) and the local solutions of nonconvex regularized QR (QR-NCP) when the number of covariates is greater than the sample size. Our results build upon and significantly generalize the…

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Transformation-Invariant Learning of Optimal Individualized Decision Rules with Time-to-Event Outcomes

事件时间结局下最优个体化决策规则的变换不变学习

In many important applications of precision medicine, the outcome of interest is time to an event (e.g., death, relapse of disease) and the primary goal is to identify the optimal individualized decision rule (IDR) to prolong survival time. Existing work in this area have been mostly focused on estimating the optimal IDR to maximize the restricted mean survival time in the population. We propose a new robust framework for estimating an optimal static or dynamic IDR with…

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Fairness-Oriented Learning for Optimal Individualized Treatment Rules

面向公平性的最优个体化处理规则学习

There has recently been a surge on the methodological development for optimal individualized treatment rule (ITR) estimation. The standard methods in the literature are designed to maximize the potential average performance (assuming larger outcomes are desirable). A notable drawback of the standard approach, due to heterogeneity in treatment response, is that the estimated optimal ITR may be suboptimal or even detrimental to certain disadvantaged subpopulations. Motivated…

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Model-Assisted Uniformly Honest Inference for Optimal Treatment Regimes in High Dimension

高维最优治疗规则的模型辅助一致诚实推断

This article develops new tools to quantify uncertainty in optimal decision making and to gain insight into which variables one should collect information about given the potential cost of measuring a large number of variables. We investigate simultaneous inference to determine if a group of variables is relevant for estimating an optimal decision rule in a high-dimensional semiparametric framework. The unknown link function permits flexible modeling of the interactions…

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High-Dimensional Quantile Regression: Convolution Smoothing and Concave Regularization

高维分位数回归:卷积平滑与凹正则化

Abstract ℓ 1 -penalized quantile regression (QR) is widely used for analysing high-dimensional data with heterogeneity. It is now recognized that the ℓ1-penalty introduces non-negligible estimation bias, while a proper use of concave regularization may lead to estimators with refined convergence rates and oracle properties as the signal strengthens. Although folded concave penalized M-estimation with strongly convex loss functions have been well studied, the extant…

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Double-slicing assisted sufficient dimension reduction for high-dimensional censored data

双重切片辅助的高维删失数据充分降维

This paper provides a unified framework and an efficient algorithm for analyzing high-dimensional survival data under weak modeling assumptions. In particular, it imposes neither parametric distributional assumption nor linear regression assumption. It only assumes that the survival time $T$ depends on a high-dimensional covariate vector $\mathbf{X}$ through low-dimensional linear combinations of covariates $\Gamma ^{T}\mathbf{X}$. The censoring time is allowed to be…

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Wild residual bootstrap inference for penalized quantile regression with heteroscedastic errors

异方差误差下惩罚分位数回归的野生残差自助推断

We consider a heteroscedastic regression model in which some of the regression coefficients are zero but it is not known which ones. Penalized quantile regression is a useful approach for analysing such data. By allowing different covariates to be relevant for modelling conditional quantile functions at different quantile levels, it provides a more complete picture of the conditional distribution of a response variable than mean regression. Existing work on penalized…

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Quantile-Optimal Treatment Regimes

分位数最优治疗规则

Finding the optimal treatment regime (or a series of sequential treatment regimes) based on individual characteristics has important applications in areas such as precision medicine, government policies and active labor market interventions. In the current literature, the optimal treatment regime is usually defined as the one that maximizes the average benefit in the potential population. This paper studies a general framework for estimating the quantile-optimal treatment…

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Estimation and Inference of Quantile Regression for Survival Data Under Biased Sampling

偏倚抽样下生存数据分位数回归的估计与推断

Biased sampling occurs frequently in economics, epidemiology, and medical studies either by design or due to data collecting mechanism. Failing to take into account the sampling bias usually leads to incorrect inference. We propose a unified estimation procedure and a computationally fast resampling method to make statistical inference for quantile regression with survival data under general biased sampling schemes, including but not limited to the length-biased sampling,…

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Partially linear additive quantile regression in ultra-high dimension

超高维部分线性可加分位数回归

We consider a flexible semiparametric quantile regression model for analyzing high dimensional heterogeneous data. This model has several appealing features: (1) By considering different conditional quantiles, we may obtain a more complete picture of the conditional distribution of a response variable given high dimensional covariates. (2) The sparsity level is allowed to be different at different quantile levels. (3) The partially linear additive structure accommodates…

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Quantile-adaptive model-free variable screening for high-dimensional heterogeneous data

高维异质数据的分位数自适应无模型变量筛选

We introduce a quantile-adaptive framework for nonlinear variable screening with high-dimensional heterogeneous data. This framework has two distinctive features: (1) it allows the set of active variables to vary across quantiles, thus making it more flexible to accommodate heterogeneity; (2) it is model-free and avoids the difficult task of specifying the form of a statistical model in a high dimensional space. Our nonlinear independence screening procedure employs spline…

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Quantile Regression for Analyzing Heterogeneity in Ultra-High Dimension

用于分析超高维异质性的分位数回归

Ultra-high dimensional data often display heterogeneity due to either heteroscedastic variance or other forms of non-location-scale covariate effects. To accommodate heterogeneity, we advocate a more general interpretation of sparsity which assumes that only a small number of covariates influence the conditional distribution of the response variable given all candidate covariates; however, the sets of relevant covariates may differ when we consider different segments of the…

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Locally Weighted Censored Quantile Regression

局部加权删失分位数回归

Censored quantile regression offers a valuable supplement to Cox proportional hazards model for survival analysis. Existing work in the literature often requires stringent assumptions, such as unconditional independence of the survival time and the censoring variable or global linearity at all quantile levels. Moreover, some of the work uses recursive algorithms, making it challenging to derive asymptotic normality. To overcome these drawbacks, we propose a new locally…

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Consistent Model Selection and Data-Driven Smooth Tests for Longitudinal Data in the Estimating Equations Approach

估计方程框架下纵向数据的一致模型选择与数据驱动光滑检验

Summary Model selection for marginal regression analysis of longitudinal data is challenging owing to the presence of correlation and the difficulty of specifying the full likelihood, particularly for correlated categorical data. The paper introduces a novel Bayesian information criterion type model selection procedure based on the quadratic inference function, which does not require the full likelihood or quasi-likelihood. With probability approaching 1, the criterion…

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