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Prediction of Random Effects in the Generalized Linear Model

广义线性模型中的随机效应预测

This article develops an estimating function-based approach to component estimation in the two-stage generalized linear model with univariate random effects and a vector of fixed effects. The novelty and unifying feature of the method is the use of estimating functions in the estimation of both the random effects and their variance. Two separate estimating procedures based on the method are proposed that differ in the intensity of numerical computation required. The…

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Multivariate Regression Analyses for Categorical Data

分类数据的多元回归分析

SUMMARY It is common to observe a vector of discrete and/or continuous responses in scientific problems where the objective is to characterize the dependence of each response on explanatory variables and to account for the association between the outcomes. The response vector can comprise repeated observations on one variable, as in longitudinal studies or genetic studies of families, or can include observations for different variables. This paper discusses a class of models…

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Conditional Logistic Regression Models for Correlated Binary Data

相关二元数据的条件Logistic回归模型

A class of conditional logistic regression models for clustered binary data is considered. This includes the polychotomous logistic model of Rosner (1984) as a special case. Properties such as the joint distribution and pairwise odds ratio are investigated. A class of easily computed estimating functions is introduced which is shown to have high efficiency compared to the computationally intensive maximum likelihood approach. An example on chronic obstructive pulmonary…

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Longitudinal data analysis using generalized linear models

使用广义线性模型分析纵向数据

This paper proposes an extension of generalized linear models to the analysis of longitudinal data. We introduce a class of estimating equations that give consistent estimates of the regression parameters and of their variance under mild assumptions about the time dependence. The estimating equations are derived without specifying the joint distribution of a subject's observations yet they reduce to the score equations for niultivariate Gaussian outcomes. Asymptotic theory…

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The analysis of binary longitudinal data with time independent covariates

具有时间不变协变量的二元纵向数据分析

This paper considers extensions of logistic regression to the case where the binary outcome variable is observed repeatedly for each subject. We propose two working models that lead to consistent estimates of the regression parameters and of their variances under mild assumptions about the time dependence within each subject's data. The efficiency of the proposed estimators is examined. An analysis of stress in mothers with infants is presented to illustrate the proposed…

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