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Bayesian Survival Analysis With Nonproportional Hazards

非比例风险下的贝叶斯生存分析

Both pravastatin and aspirin are approved by the U.S. Food and Drug Administration (FDA) for secondary prevention of cardiovascular events. This article describes statistical analyses used for a successful submission to the FDA that contends that copackaging pravastatin and aspirin provides a health benefit. From the efficacy perspective this is taken to mean that the combination is more effective than either agent considered alone. We present three Bayesian hierarchical…

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Generalized Linear Models for Small-Area Estimation

用于小区域估计的广义线性模型

Bayesian methods have been used quite extensively in recent years for solving small-area estimation problems. Particularly effective in this regard has been the hierarchical or empirical Bayes approach, which is especially suitable for a systematic connection of local areas through models. However, the development to date has mainly concentrated on continuous-valued variates. Often the survey data are discrete or categorical, so that hierarchical or empirical Bayes…

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