Judith ter Schure’s contribution to the Discussion of ‘Safe testing’ by Grünwald, de Heide, and Koolen
Judith ter Schure 对《安全检验》的讨论
Once there was a randomized controlled trial (RCT) that studied the recurrence of stroke. It had assumed for the treatment of interest a 40% reduction in hazard, and had set the sample size accordingly (Kamel et al., 2024). The RCT found a 95% confidence interval of (−55%, 36%) and concluded no statistical significance. ‘Absence of evidence is not evidence of absence’ said the statisticians (Altman & Bland, 1995; Harrell, 2024). But the story goes that the sample size was…