Inference for Subgroup Analysis With a Structured Logistic-Normal Mixture Model
结构化 logistic–normal 混合模型的亚组分析推断
In this article, we propose a statistical model for the purpose of identifying a subgroup that has an enhanced treatment effect as well as the variables that are predictive of the subgroup membership. The need for such subgroup identification arises in clinical trials and in market segmentation analysis. By using a structured logistic-normal mixture model, our proposed framework enables us to perform a confirmatory statistical test for the existence of subgroups, and at the…