Smoothing Spline Models for the Analysis of Nested and Crossed Samples of Curves
嵌套与交叉曲线样本分析的平滑样条模型
We introduce a class of models for an additive decomposition of groups of curves stratified by crossed and nested factors, generalizing smoothing splines to such samples by associating them with a corresponding mixed-effects model. The models are also useful for imputation of missing data and exploratory analysis of variance. We prove that the best linear unbiased predictors (BLUPs) from the extended mixed-effects model correspond to solutions of a generalized penalized…