Testing Disease Dependence in Survival Experiments with Serial Sacrifice
含分期处死设计的生存实验中疾病依赖性的检验
An age-dependent compartment model is applied in a novel way to survival data. Analysis is performed of data from an “improved survival experiment” which incorporates serial sacrifice, and tests of hypotheses of dependent diseases are obtained. Problems dealing with identifiability of models are emphasized and discussed. Finally, these ideas are illustrated in connection with experimental data from mice exposed to radiation.