Robust Estimation for Homoscedastic Regression in the Secondary Analysis of Case–Control Data
病例对照数据二次分析中同方差回归的稳健估计
Summary Primary analysis of case–control studies focuses on the relationship between disease D and a set of covariates of interest (Y, X). A secondary application of the case–control study, which is often invoked in modern genetic epidemiologic association studies, is to investigate the interrelationship between the covariates themselves. The task is complicated owing to the case–control sampling, where the regression of Y on X is different from what it is in the population.…