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Semiparametric Estimation of Covariance Matrixes for Longitudinal Data

纵向数据协方差矩阵的半参数估计

Estimation of longitudinal data covariance structure poses significant challenges because the data are usually collected at irregular time points. A viable semiparametric model for covariance matrices was proposed in Fan, Huang and Li (2007) that allows one to estimate the variance function nonparametrically and to estimate the correlation function parametrically via aggregating information from irregular and sparse data points within each subject. However, the asymptotic…

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High-dimensional classification using features annealed independence rules

基于特征筛减独立规则的高维分类

Classification using high-dimensional features arises frequently in many contemporary statistical studies such as tumor classification using microarray or other high-throughput data. The impact of dimensionality on classifications is largely poorly understood. In a seminal paper, Bickel and Levina (2004) show that the Fisher discriminant performs poorly due to diverging spectra and they propose to use the independence rule to overcome the problem. We first demonstrate that…

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Sure Independence Screening for Ultrahigh Dimensional Feature Space

超高维特征空间的确定性独立筛选

Summary Variable selection plays an important role in high dimensional statistical modelling which nowadays appears in many areas and is key to various scientific discoveries. For problems of large scale or dimensionality p, accuracy of estimation and computational cost are two top concerns. Recently, Candes and Tao have proposed the Dantzig selector using L1-regularization and showed that it achieves the ideal risk up to a logarithmic factor log(p). Their innovative…

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High dimensional covariance matrix estimation using a factor model

使用因子模型估计高维协方差矩阵

High dimensionality comparable to sample size is common in many statistical problems. We examine covariance matrix estimation in the asymptotic framework that the dimensionality p tends to [infinity] as the sample size n increases. Motivated by the Arbitrage Pricing Theory in finance, a multi-factor model is employed to reduce dimensionality and to estimate the covariance matrix. The factors are observable and the number of factors K is allowed to grow with p. We investigate…

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Profile-kernel likelihood inference with diverging number of parameters

参数维数增长时的剖面核似然推断

The generalized varying coefficient partially linear model with growing number of predictors arises in many contemporary scientific endeavor. In this paper we set foot on both theoretical and practical sides of profile likelihood estimation and inference. When the number of parameters grows with sample size, the existence and asymptotic normality of the profile likelihood estimator are established under some regularity conditions. Profile likelihood ratio inference for the…

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Modelling Multivariate Volatilities via Conditionally Uncorrelated Components

利用条件不相关分量建模多元波动率

Summary We propose to model multivariate volatility processes on the basis of the newly defined conditionally uncorrelated components (CUCs). This model represents a parsimonious representation for matrix-valued processes. It is flexible in the sense that each CUC may be fitted separately with any appropriate univariate volatility model. Computationally it splits one high dimensional optimization problem into several lower dimensional subproblems. Consistency for the…

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Partially Linear Hazard Regression with Varying Coefficients for Multivariate Survival Data

多元生存数据的变系数部分线性风险回归

Summary The paper studies estimation of partially linear hazard regression models with varying coefficients for multivariate survival data. A profile pseudo-partial-likelihood estimation method is proposed. The estimation of the parameters of the linear part is accomplished via maximization of the profile pseudo-partial-likelihood, whereas the varying-coefficient functions are considered as nuisance parameters that are profiled out of the likelihood. It is shown that the…

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To How Many Simultaneous Hypothesis Tests Can Normal, Student's t or Bootstrap Calibration Be Applied?

正态、Student t与bootstrap校准可支持多少个同时假设检验?

In the analysis of microarray data, and in some other contemporary statistical problems, it is not uncommon to apply hypothesis tests in a highly simultaneous way. The number, N say, of tests used can be much larger than the sample sizes, n, to which the tests are applied, yet we wish to calibrate the tests so that the overall level of the simultaneous test is accurate. Often the sampling distribution is quite different for each test, so there may not be an opportunity to…

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Multi-Scale Jump and Volatility Analysis for High-Frequency Financial Data

高频金融数据的多尺度跳跃与波动率分析

The wide availability of high-frequency data for many financial instruments stimulates an upsurge interest in statistical research on the estimation of volatility. Jump-diffusion processes observed with market microstructure noise are frequently used to model high-frequency financial data. Yet existing methods are developed for either noisy data from a continuous-diffusion price model or data from a jump-diffusion price model without noise. We propose methods to cope with…

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Partially Linear Hazard Regression for Multivariate Survival Data

多变量生存数据的部分线性风险回归

This article studies estimation of partially linear hazard regression models for multivariate survival data. A profile pseudo–partial likelihood estimation method is proposed under the marginal hazard model framework. The estimation on the parameters for the linear part is accomplished by maximization of a pseudo–partial likelihood profiled over the nonparametric part. This enables us to obtain -consistent estimators of the parametric component. Asymptotic normality is…

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Dynamic Integration of Time- and State-Domain Methods for Volatility Estimation

波动率估计中时间域与状态域方法的动态整合

Time- and state-domain methods are two common approaches to nonparametric prediction. Whereas the former uses data predominantly from recent history, the latter relies mainly on historical information. Combining these two pieces of valuable information is an interesting challenge in statistics. We surmount this problem by dynamically integrating information from both the time and state domains. The estimators from these two domains are optimally combined based on a…

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Analysis of Longitudinal Data With Semiparametric Estimation of Covariance Function

协方差函数半参数估计下的纵向数据分析

Improving efficiency for regression coefficients and predicting trajectories of individuals are two important aspects in analysis of longitudinal data. Both involve estimation of the covariance function. Yet, challenges arise in estimating the covariance function of longitudinal data collected at irregular time points. A class of semiparametric models for the covariance function is proposed by imposing a parametric correlation structure while allowing a nonparametric…

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Hazard models with varying coefficients for multivariate failure time data

多元失效时间数据的变系数风险模型

Statistical estimation and inference for marginal hazard models with varying coefficients for multivariate failure time data are important subjects in survival analysis. A local pseudo-partial likelihood procedure is proposed for estimating the unknown coefficient functions. A weighted average estimator is also proposed in an attempt to improve the efficiency of the estimator. The consistency and asymptotic normality of the proposed estimators are established and standard…

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Local partial-likelihood estimation for lifetime data

生存时间数据的局部部分似然估计

This paper considers a proportional hazards model, which allows one to examine the extent to which covariates interact nonlinearly with an exposure variable, for analysis of lifetime data. A local partial-likelihood technique is proposed to estimate nonlinear interactions. Asymptotic normality of the proposed estimator is established. The baseline hazard function, the bias and the variance of the local likelihood estimator are consistently estimated. In addition, a one-step…

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Semilinear High-Dimensional Model for Normalization of Microarray Data

微阵列数据归一化的半线性高维模型

Normalization of microarray data is essential for removing experimental biases and revealing meaningful biological results. Motivated by a problem of normalizing microarray data, a semilinear in-slide model (SLIM) has been proposed. To aggregate information from other arrays, SLIM is generalized to account for across-array information, resulting in an even more dynamic semiparametric regression model. This model can be used to normalize microarray data even when there is no…

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Nonparametric Inferences for Additive Models

加性模型的非参数推断

Additive models with backfitting algorithms are popular multivariate nonparametric fitting techniques. However, the inferences of the models have not been very well developed, due partially to the complexity of the backfitting estimators. There are few tools available to answer some important and frequently asked questions, such as whether a specific additive component is significant or admits a certain parametric form. In an attempt to address these issues, we extend the…

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Variable selection for multivariate failure time data

多元失效时间数据的变量选择

In this paper, we proposed a penalised pseudo-partial likelihood method for variable selection with multivariate failure time data with a growing number of regression coefficients. Under certain regularity conditions, we show the consistency and asymptotic normality of the penalised likelihood estimators. We further demonstrate that, for certain penalty functions with proper choices of regularisation parameters, the resulting estimator can correctly identify the true model,…

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Sieve empirical likelihood ratio tests for nonparametric functions

非参数函数的筛经验似然比检验

Generalized likelihood ratio statistics have been proposed in Fan, Zhang and Zhang [Ann. Statist. 29 (2001) 153–193] as a generally applicable method for testing nonparametric hypotheses about nonparametric functions. The likelihood ratio statistics are constructed based on the assumption that the distributions of stochastic errors are in a certain parametric family. We extend their work to the case where the error distribution is completely unspecified via newly proposed…

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New Estimation and Model Selection Procedures for Semiparametric Modeling in Longitudinal Data Analysis

纵向数据半参数建模的新估计与模型选择程序

Semiparametric regression models are very useful for longitudinal data analysis. The complexity of semiparametric models and the structure of longitudinal data pose new challenges to parametric inferences and model selection that frequently arise from longitudinal data analysis. In this article, two new approaches are proposed for estimating the regression coefficients in a semiparametric model. The asymptotic normality of the resulting estimators is established. An…

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Nonconcave penalized likelihood with a diverging number of parameters

参数维度随样本量增长的非凹惩罚似然

A class of variable selection procedures for parametric models via nonconcave penalized likelihood was proposed by Fan and Li to simultaneously estimate parameters and select important variables. They demonstrated that this class of procedures has an oracle property when the number of parameters is finite. However, in most model selection problems the number of parameters should be large and grow with the sample size. In this paper some asymptotic properties of the…

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Semiparametric estimation of Value at Risk

风险价值的半参数估计

Value at Risk (VaR) is a fundamental tool for managing market risks. It measures the worst loss to be expected of a portfolio over a given time horizon under normal market conditions at a given confidence level. Calculation of VaR frequently involves estimating the volatility of return processes and quantiles of standardized returns. In this paper, several semiparametric techniques are introduced to estimate the volatilities of the market prices of a portfolio. In addition,…

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A Reexamination of Diffusion Estimators With Applications to Financial Model Validation

扩散估计量的重新审视及其在金融模型检验中的应用

Time-homogeneous diffusion models have been widely used for describing the stochastic dynamics of the underlying economic variables. Recently, Stanton proposed drift and diffusion estimators based on a higher-order approximation scheme and kernel regression method. He claimed that “higher order approximations must outperform lower order approximations” and concluded nonlinearity in the instantaneous return function of short-term interest rates. To examine the impact of…

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Adaptive Varying-Coefficient Linear Models

自适应变系数线性模型

Summary Varying-coefficient linear models arise from multivariate nonparametric regression, non-linear time series modelling and forecasting, functional data analysis, longitudinal data analysis and others. It has been a common practice to assume that the varying coefficients are functions of a given variable, which is often called an index. To enlarge the modelling capacity substantially, this paper explores a class of varying-coefficient linear models in which the index is…

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Variable Selection for Cox's proportional Hazards Model and Frailty Model

Cox 比例风险模型与脆弱性模型的变量选择

A class of variable selection procedures for parametric models via nonconcave penalized likelihood was proposed in Fan and Li (2001a). It has been shown there that the resulting procedures perform as well as if the subset of significant variables were known in advance. Such a property is called an oracle property. The proposed procedures were illustrated in the context of linear regression, robust linear regression and generalized linear models. In this paper, the nonconcave…

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