Risk Classification With an Adaptive Naive Bayes Kernel Machine Model
基于自适应朴素贝叶斯核机器模型的疾病风险分类
Genetic studies of complex traits have uncovered only a small number of risk markers explaining a small fraction of heritability and adding little improvement to disease risk prediction. Standard single marker methods may lack power in selecting informative markers or estimating effects. Most existing methods also typically do not account for non-linearity. Identifying markers with weak signals and estimating their joint effects among many non-informative markers remains…