论文检索

探索效应修饰的观察性研究中族错误率的强控制AI 解读

An effect modifier is a pretreatment covariate that affects the magnitude of the treatment effect or its stability. When there is effect modification, an overall test that ignores an effect modifier may be more sensitive to unmeasured bias than a test that combines results from subgroups defined by the effect modifier. If there is effect modification, one would like to identify specific subgroups for which there is evidence of effect that is insensitive to small or moderate…

观察性研究中的效应修饰与设计敏感性AI 解读

In an observational study of treatment effects, subjects are not randomly assigned to treatment or control, so differing outcomes in treated and control groups may reflect a bias from nonrandom assignment rather than a treatment effect. After adjusting for measured pretreatment covariates, perhaps by matching, a sensitivity analysis determines the magnitude of bias from an unmeasured covariate that would need to be present to alter the conclusions of the naive analysis that…