Inferring Spatial Phylogenetic Variation Along Nucleotide Sequences
核苷酸序列沿线系统发育变异的推断
We develop a Bayesian multiple changepoint model to infer spatial phylogenetic variation (SPV) along aligned molecular sequence data. SPV occurs in sequences from organisms that have undergone biological recombination or when evolutionary rates and selective pressures vary along the sequences. This Bayesian approach permits estimation of uncertainty regarding recombination, the crossing-over locations, and all other model parameters. The model assumes that the sites along…