Efficient estimation of the prevalence of multiple rare traits
多种稀有特征流行比例的有效估计
We consider a population with multiple traits of interest, where our goal is to estimate the proportions of individuals with the traits. When traits are rare, group testing can improve efficiency. Previous work of Hughes-Oliver & Swallow (1994) developed an adaptive two-stage design for group testing of only one trait. We extend this work to the multi-trait case. We derive the optimum group sizes using compound D-optimum design theory. Estimation is based on maximum…