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基于参数 Copula 的依赖删失模型AI 解读

Summary Consider a survival time $T$ that is subject to random right censoring, and suppose that $T$ is stochastically dependent on the censoring time $C$. We are interested in the marginal distribution of $T$. This situation is often encountered in practice. Consider, for example, the case where $T$ is a patient’s time to death from a certain disease. Then the censoring time $C$ could be the time until the patient leaves the study or the time until death from another cause.…

依赖删失生存数据的半参数建模、估计与推断AI 解读

Summary When modelling survival data, it is common to assume that the survival time $T$ is conditionally independent of the censoring time $C$ given a set of covariates. However, there are numerous situations in which this assumption is not realistic. The goal of this paper is therefore to develop a semiparametric normal transformation model which assumes that, after a proper nonparametric monotone transformation, the vector $(T, C)$ follows a linear model, and the vector of…

利用 ROC 曲线评估生存数据中的治愈状态预测AI 解读

Summary Survival analysis relies on the hypothesis that, if the follow-up is long enough, the event of interest will eventually be observed for all observations. This assumption, however, is often not realistic. The survival data then contain a cure fraction. A common approach to modelling and analysing this type of data consists in using cure models. Two types of information can therefore be obtained: the survival at a given time and the cure status, both possibly modelled…

回归残差过程的自助法：是否需要平滑？AI 解读

In this paper we consider a location model of the form $Y = m(X) + \varepsilon$, where $m(\cdot)$ is the unknown regression function, the error $\varepsilon$ is independent of the $p$-dimensional covariate $X$ and $E(\varepsilon)=0$. Given i.i.d. data $(X_1,Y_1),\ldots,(X_n,Y_n)$ and given an estimator $\hat m(\cdot)$ of the function $m(\cdot)$ (which can be parametric or nonparametric of nature), we estimate the distribution of the error term $\varepsilon$ by the empirical…

混合治愈模型中治愈率的拟合优度检验AI 解读

We consider models for time-to-event data that allow that an event, e.g., a relapse of a disease, never occurs for a certain percentage |$p$| of the population, called the cure rate. We suppose that these data are subject to random right censoring and we model the data using a mixture cure model, in which the survival function of the uncured subjects is left unspecified. The aim is to test whether the cure rate |$p$|⁠, as a function of the covariates, satisfies a certain…