A Statistical Framework to Infer Functional Gene Relationships From Biologically Interrelated Microarray Experiments
从生物关联微阵列实验推断基因功能关系的统计框架
A major task in understanding biological processes is to elucidate the relationships between genes involved in the underlying biological pathways. Microarray data from an increasing number of biologically interrelated experiments now allows for more complete portrayals of functional gene relationships in the pathways. In current studies of gene relationships, the presence of expression dependencies attributable to the biologically interrelated experiments, however, has been…