A Bayesian Hierarchical CACE Model Accounting for Incomplete Noncompliance With Application to a Meta-analysis of Epidural Analgesia on Cesarean Section
处理不完整依从信息的贝叶斯分层 CACE 模型:硬膜外镇痛与剖宫产的荟萃分析
Noncompliance with assigned treatments is a common challenge in analyzing and interpreting randomized clinical trials (RCTs). One way to handle noncompliance is to estimate the complier-average causal effect (CACE), the intervention's efficacy in the subpopulation that complies with assigned treatment. In a two-step meta-analysis, one could first estimate CACE for each study, then combine them to estimate the population-averaged CACE. However, when some trials do not report…