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利用树状收缩多结局回归估计细颗粒物与432种心血管疾病的关系AI 解读

The positive relationship between airborne fine particulate matter (PM2.5) and cardiovascular disease (CVD) is established. Little is known about effect size heterogeneity across distinct CVD outcomes. We conducted a multi-outcome case-crossover study of Medicare beneficiaries aged >65 years residing in the mainland USA from 2000 through 2012. The exposure was two-day average PM2.5 in each individual’s residential zipcode. The outcomes were hospitalization for 432 distinct…

偏头痛治疗的元分析：融合异质研究设计的信息AI 解读

Migraine headache is a common condition in the United States for which a wide range of drug and nondrug treatments are available. There is wide disagreement about which treatments are most effective; meta-analysis of existing clinical trials can help to bring existing evidence to bear on this question. Conducting a meta-analysis is a challenging statistical problem because of the absence of a uniform accepted definition of headache syndromes, the diversity of treatments, and…