Nonparametric Causal Inference for Optogenetics: Sequential Excursion Effects for Dynamic Regimes
光遗传学的非参数因果推断:动态策略的序贯偏离效应
Optogenetics is a powerful neuroscience technique for studying how neural circuit manipulation affects behavior. Standard analysis conventions discard information and severely limit the scope of the causal questions that can be probed. To address this gap, we 1) draw connections to the causal inference literature on sequentially randomized experiments, 2) propose a non-parametric framework for analyzing "open-loop" (static regime) optogenetics behavioral experiments, 3)…