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含测量误差的高维泊松模型：非线性非凸优化中的假设检验AI 解读

We study estimation and testing in the Poisson regression model with noisy high-dimensional covariates, which has wide applications in analyzing noisy big data. Correcting for the estimation bias due to the covariate noise leads to a nonconvex target function to minimize. Treating the high-dimensional issue further leads us to augment an amenable penalty term to the target function. We propose to estimate the regression parameter through minimizing the penalized target…

函数型删失分位数回归AI 解读

We propose a functional censored quantile regression model to describe the time-varying relationship between time-to-event outcomes and corresponding functional covariates. The time-varying effect is modeled as an unspecified function that is approximated via B-splines. A generalized approximate cross-validation method is developed to select the number of knots by minimizing the expected loss. We establish asymptotic properties of the method and the knot selection procedure.…

随机比较研究中估计处理效应的稳健 ANCOVA 替代方法AI 解读

In comparing two treatments via a randomized clinical trial, the analysis of covariance (ANCOVA) technique is often utilized to estimate an overall treatment effect. The ANCOVA is generally perceived as a more efficient procedure than its simple two sample estimation counterpart. Unfortunately, when the ANCOVA model is nonlinear, the resulting estimator is generally not consistent. Recently, various nonparametric alternatives to the ANCOVA, such as the augmentation methods,…

重复测量结果的函数单指标广义部分线性模型：核与样条融合平滑AI 解读

We propose a generalized partially linear functional single index risk score model for repeatedly measured outcomes where the index itself is a function of time. We fuse the nonparametric kernel method and regression spline method, and modify the generalized estimating equation to facilitate estimation and inference. We use local smoothing kernel to estimate the unspecified coefficient functions of time, and use B-splines to estimate the unspecified function of the single…