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乘积形式特征分配模型的贝叶斯分析AI 解读

Abstract Feature allocation models are an extension of Bayesian nonparametric clustering models, where individuals can share multiple features. We study a broad class of models whose probability distribution has a product form, which includes the popular Indian buffet process. This class plays a prominent role among existing priors, and it shares structural characteristics with Gibbs-type priors in the species sampling framework. We develop a general theory for the entire…

具有排斥与吸引原子的贝叶斯混合模型AI 解读

Abstract The study of almost surely discrete random probability measures is an active line of research in Bayesian non-parametrics. The idea of assuming interaction across the atoms of the random probability measure has recently spurred significant interest in the context of Bayesian mixture models. This allows the definition of priors that encourage well-separated and interpretable clusters. In this work, we provide a unified framework for the construction and the Bayesian…

用于未观测遗传变异估计的贝叶斯非参数缩放过程先验AI 解读

There is a growing interest in the estimation of the number of unseen features, mostly driven by biological applications. A recent work brought out a peculiar property of the popular completely random measures (CRMs) as prior models in Bayesian nonparametric (BNP) inference for the unseen-features problem: for fixed prior's parameters, they all lead to a Poisson posterior distribution for the number of unseen features, which depends on the sampling information only through…

用于嵌套数据贝叶斯非参数分析的共同原子模型AI 解读

The use of large datasets for targeted therapeutic interventions requires new ways to characterize the heterogeneity observed across subgroups of a specific population. In particular, models for partially exchangeable data are needed for inference on nested datasets, where the observations are assumed to be organized in different units and some sharing of information is required to learn distinctive features of the units. In this manuscript, we propose a nested common atoms…

以更少资源发现更多基因变异：贝叶斯非参数预测与优化AI 解读

Summary While the cost of sequencing genomes has decreased dramatically in recent years, this expense often remains nontrivial. Under a fixed budget, scientists face a natural trade-off between quantity and quality: spending resources to sequence a greater number of genomes or spending resources to sequence genomes with increased accuracy. Our goal is to find the optimal allocation of resources between quantity and quality. Optimizing resource allocation promises to reveal…

基于层次依赖混合风险率的生存分析AI 解读

Hierarchical nonparametric processes are popular tools for defining priors on collections of probability distributions, which induce dependence across multiple samples. In survival analysis problems, one is typically interested in modeling the hazard rates, rather than the probability distributions themselves, and the currently available methodologies are not applicable. Here, we fill this gap by introducing a novel, and analytically tractable, class of multivariate mixtures…

最优数据披露风险评估AI 解读

Protection against disclosure is a legal and ethical obligation for agencies releasing microdata files for public use. Consider a microdata sample of size n from a finite population of size n¯=n+λn, with λ>0, such that each sample record contains two disjoint types of information: identifying categorical information and sensitive information. Any decision about releasing data is supported by the estimation of measures of disclosure risk, which are defined as discrete…

层级随机过程的分布理论AI 解读

Hierarchies of discrete probability measures are remarkably popular as nonparametric priors in applications, arguably due to two key properties: (i) they naturally represent multiple heterogeneous populations; (ii) they produce ties across populations, resulting in a shrinkage property often described as “sharing of information.” In this paper, we establish a distribution theory for hierarchical random measures that are generated via normalization, thus encompassing both the…