Transmission of Pneumococcal Carriage in Families: A Latent Markov Process Model for Binary Longitudinal Data
家庭内肺炎链球菌携带传播:二元纵向数据的潜在马尔可夫过程模型
We present a Bayesian data augmentation model to estimate acquisition and clearance rates of carriage of Streptococcus pneumoniae (Pnc) bacteria. The panel observation data comprise 10 measurements of Pnc carriage (carrier/noncarrier of the bacteria) in all members of 97 families with young children over a period of 2 years. Using natural conditional independence assumptions, a transmission model is constructed for the unobserved dependent binary processes of the augmented…