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Principal Stratification for Causal Inference With Extended Partial Compliance

扩展部分依从情形下因果推断的主层化方法

Many double-blind placebo-controlled randomized experiments with active drugs suffer from complications beyond simple noncompliance. First, the compliance with assigned dose is often partial, with patients taking only part of the assigned dose, whether active or placebo. Second, the blinding may be imperfect in the sense that there may be detectable positive or negative side effects of the active drug, and consequently, simple compliance has to be extended to allow different…

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Causal Inference Using Potential Outcomes

使用潜在结果进行因果推断

Causal effects are defined as comparisons of potential outcomes under different treatments on a common set of units. Observed values of the potential outcomes are revealed by the assignment mechanism—a probabilistic model for the treatment each unit receives as a function of covariates and potential outcomes. Fisher made tremendous contributions to causal inference through his work on the design of randomized experiments, but the potential outcomes perspective applies to…

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Iterative Automated Record Linkage Using Mixture Models

利用混合模型迭代开展自动记录链接

The goal of record linkage is to link quickly and accurately records that correspond to the same person or entity. Whereas certain patterns of agreements and disagreements on variables are more likely among records pertaining to a single person than among records for different people, the observed patterns for pairs of records can be viewed as arising from a mixture of matches and nonmatches. Mixture model estimates can be used to partition record pairs into two or more…

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