Reducing the Use of Laboratory Animals in Toxicological Research and Testing by Better Experimental Design
通过改进实验设计减少毒理研究与测试中的动物使用
SUMMARY More than 50 million animals are used in biomedical research in the world each year. It is highly desirable that this number is reduced both for ethical and for economic reasons. Better experimental design could lead to the use of fewer animals and improve the repeatability of animal experiments so that alternative methods would be easier to validate. Screening experiments aimed at identifying rodent carcinogens would be more powerful if more than one strain of mice…